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视觉适应与视锥细胞闪烁视网膜电图

Visual adaptation and the cone flicker electroretinogram.

作者信息

Peachey N S, Alexander K R, Fishman G A

机构信息

Department of Ophthalmology, University of Illinois Chicago College of Medicine.

出版信息

Invest Ophthalmol Vis Sci. 1991 Apr;32(5):1517-22.

PMID:2016133
Abstract

This study examined the hypothesis that changes in the response properties of the human cone ERG during light adaptation represent the recovery of cone system responsiveness toward a dark-adapted value after an initial decrease in responsiveness at adapting field onset. The electroretinographic (ERG) responses to 31.1 Hz flicker were obtained under both dark-adapted and light-adapted conditions for stimulus luminances ranging from -1.42(-)+0.82 log cd sec/m2. At low stimulus luminances, flicker ERG amplitudes were larger under dark-adapted than under light-adapted conditions, consistent with the hypothesis. However, at high stimulus luminances, flicker ERG amplitudes obtained under light-adapted conditions were approximately double those recorded from the dark-adapted eye. Therefore, the increase in cone ERG amplitude that occurs during light adaptation at high stimulus luminances does not represent a return toward a dark-adapted level but instead entails a substantial enhancement above the dark-adapted value, by a mechanism that is presently unidentified.

摘要

本研究检验了这样一种假设

在明适应过程中,人眼视锥细胞视网膜电图(ERG)反应特性的变化代表了在适应场开始时反应性最初下降之后,视锥系统反应性朝着暗适应值的恢复。在暗适应和明适应条件下,针对范围从-1.42(±)0.82 log cd·sec/m²的刺激亮度,获得了对31.1 Hz闪烁的视网膜电图(ERG)反应。在低刺激亮度下,暗适应条件下的闪烁ERG振幅比明适应条件下的更大,这与该假设一致。然而,在高刺激亮度下,明适应条件下获得的闪烁ERG振幅约为暗适应眼记录值的两倍。因此,在高刺激亮度的明适应过程中发生的视锥细胞ERG振幅增加并不代表朝着暗适应水平的恢复,而是通过目前尚不清楚的机制,在暗适应值之上有实质性增强。

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