利用重氮磺酸盐C-H插入反应构建季碳中心对补骨脂酚进行对映选择性合成。
Enantioselective synthesis of Bakuchiol using diazosulfonate C-H insertion to install the quaternary center.
作者信息
Bequette Joseph P, Jungong Christian S, Novikov Alexei V
机构信息
University of North Dakota, 151 Cornell St. Stop 9024, Grand Forks, ND 58202, USA.
出版信息
Tetrahedron Lett. 2009 Dec 16;50(50):6963-6964. doi: 10.1016/j.tetlet.2009.09.147.
Abstract
Bakuchiol was prepared from commercial (-)-citronellol using the diazosulfonate C-H insertion to control the regioselectivity and install the quaternary center.
摘要
补骨脂酚是由市售的（-）-香茅醇通过重氮磺酸盐的C-H插入反应制得，以控制区域选择性并构建季碳中心。
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