干细胞：有多种选择是好事。

Stem Cells: It's Good To Have Choices.

作者信息

Bellayr Ian H, Li Yong

机构信息

Children's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA, USA ; University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

J Am Col Certif Wound Spec. 2009 Jun 23;1(3):92-4. doi: 10.1016/j.jcws.2009.05.004.

DOI:10.1016/j.jcws.2009.05.004

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2801919/

Abstract

Three types of stem cells, embryonic, adult, and induced pluripotent stem cells, are currently studied by scientists. Barack Obama's presidency has opened the door for stem cell research by revoking statements and orders made during the former President Bush's administration. This provisional period will allow the National Institute of Health to rewrite policies governing how federal funds are distributed for stem cell research. These new regulations will grant more freedom to researchers wishing to use stem cells in their research and challenge them to determine the most appropriate stem cell treatment for a given disorder.

摘要

目前，科学家们正在研究三种类型的干细胞，即胚胎干细胞、成体干细胞和诱导多能干细胞。巴拉克·奥巴马担任总统期间，撤销了前总统布什政府发布的声明和命令，为干细胞研究打开了大门。这一过渡时期将使美国国立卫生研究院能够重新制定关于联邦资金如何分配用于干细胞研究的政策。这些新规定将给予希望在研究中使用干细胞的研究人员更多自由，并促使他们确定针对特定疾病最合适的干细胞治疗方法。

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Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds.利用Oct4和Klf4与小分子化合物从小鼠胚胎成纤维细胞诱导多能干细胞。

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Induced pluripotent stem cells generated without viral integration.无病毒整合产生的诱导多能干细胞。

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PTHrP promotes chondrogenesis and suppresses hypertrophy from both bone marrow-derived and adipose tissue-derived MSCs.甲状旁腺激素相关蛋白（PTHrP）可促进骨髓来源和脂肪组织来源的间充质干细胞（MSC）的软骨生成并抑制其肥大。

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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.从小鼠和人成纤维细胞中生成不含Myc的诱导多能干细胞。

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Induced pluripotent stem cell lines derived from human somatic cells.源自人类体细胞的诱导多能干细胞系。

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