Shvartzman P, Swartz T, Stopler T, Herman J
Department of Family Medicine, Faculty of Health Sciences, Ben-Gurion University of Negev, Beer Sheva, Israel.
Isr J Med Sci. 1991 Mar;27(3):137-40.
An outbreak of pertussis encompassing 78 cases in a population of 964 persons living on kibbutz is described. The attack rate was 36.1% among children aged 4 to 11 years, although all had been fully vaccinated. Female predominance and seasonal incidence conformed with what has been reported in the literature. The age distribution, however, was markedly different from that usually observed, indicating that local factors may influence the epidemiology of whooping cough. Despite the seeming paradox of the disease breaking out in a population with a high immunization rate, our results suggest that the vaccine had a protective effect in all age-groups. The incidence of pertussis in Israel in 1987 was considerably higher than that in the United States for the same year, and raises the question of changing the recommendations for vaccination here.
本文描述了在一个基布兹（集体农场）的964名居民中发生的一场百日咳疫情，共有78例病例。4至11岁儿童的罹患率为36.1%，尽管他们都已全程接种疫苗。女性为主以及季节性发病率与文献报道相符。然而，年龄分布与通常观察到的情况明显不同，表明当地因素可能影响百日咳的流行病学特征。尽管在高免疫率人群中出现了这种疾病似乎自相矛盾，但我们的结果表明该疫苗在所有年龄组均有保护作用。1987年以色列的百日咳发病率大大高于同年美国的发病率，这引发了改变此地疫苗接种建议的问题。
