Binkin N J, Salmaso S, Tozzi A E, Scuderi G, Greco D, Greco D
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
Pediatr Infect Dis J. 1992 Aug;11(8):653-61.
In Italy pertussis vaccination is optional. Fewer than 40% of children younger than 5 years of age are vaccinated, and pertussis remains a common childhood disease. We use data from a variety of sources to examine trends and characteristics of Italian children with pertussis and reasons behind the low vaccine coverage. Approximately 25% of Italian children have experienced clinical pertussis by their fifth birthday. The disease is most severe in those less than 1 year of age; in this group an estimated 1 in 14 cases are hospitalized and 1 in 850 die. The incidence appears to be increasing in the 1- to 4-year age group despite increased vaccination coverage. The low vaccine coverage appears to be caused by the ambivalence of the Italian pediatric community about the vaccine rather than parental concerns about vaccine safety. Legislation is being considered to make pertussis vaccination mandatory.
在意大利，百日咳疫苗接种是可选择的。5岁以下儿童中接种疫苗的不到40%，百日咳仍是一种常见的儿童疾病。我们使用来自各种来源的数据来研究意大利百日咳患儿的趋势和特征以及疫苗接种率低的原因。约25%的意大利儿童在5岁生日前经历过临床百日咳。该疾病在1岁以下儿童中最为严重；在这个年龄组中，估计每14例病例中有1例住院，每850例中有1例死亡。尽管疫苗接种率有所提高，但1至4岁年龄组的发病率似乎仍在上升。疫苗接种率低似乎是由于意大利儿科界对该疫苗态度矛盾，而非家长对疫苗安全性的担忧。目前正在考虑立法强制进行百日咳疫苗接种。
