Maayan S, Morali G, Engelhard D, Akerman Z, Gez E, Shapiro M, Bercovier H, Sacks T
Department of Clinical Microbiology, Hadassah University Hospital, Jerusalem, Israel.
Isr J Med Sci. 1991 Mar;27(3):145-9.
During 1985 in the Hadassah University Hospital we studied all hospitalized patients whose serum had been submitted for Legionella antibodies. Of 133 patients, 12 (9%) had legionellosis as diagnosed by serology, direct fluorescence, or culture. All Legionella cases appeared to be sporadic, nonseasonal, community-acquired pneumonia. There were no specific environmental co-factors or clustering. A significant predilection of the disease for immunosuppressed individuals was observed; the in-hospital mortality was high (5/12), especially if erythromycin therapy was delayed. L. pneumophila and L. bozemanii were the dominant etiological species. In Jerusalem, Legionella is not infrequently the etiological agent in community-acquired pneumonia in immunosuppressed patients.
1985年期间,我们在哈达萨大学医院研究了所有血清送检检测军团菌抗体的住院患者。在133例患者中,有12例(9%)经血清学、直接荧光检测或培养确诊为军团菌病。所有军团菌病例似乎均为散发性、非季节性、社区获得性肺炎。不存在特定的环境协同因素或聚集现象。观察到该疾病对免疫抑制个体有明显的偏好;住院死亡率很高(12例中有5例),尤其是在红霉素治疗延迟的情况下。嗜肺军团菌和博兹曼军团菌是主要的病原体。在耶路撒冷,军团菌在免疫抑制患者社区获得性肺炎中经常是病原体。