生物医学和牙科植入物的表面改性以及炎症、伤口愈合和骨形成的过程。
Surface modification of biomedical and dental implants and the processes of inflammation, wound healing and bone formation.
机构信息
Dows Institute for Dental Research, University of Iowa, 52242, USA.
出版信息
Int J Mol Sci. 2010 Jan 25;11(1):354-69. doi: 10.3390/ijms11010354.
Abstract
Bone adaptation or integration of an implant is characterized by a series of biological reactions that start with bone turnover at the interface (a process of localized necrosis), followed by rapid repair. The wound healing response is guided by a complex activation of macrophages leading to tissue turnover and new osteoblast differentiation on the implant surface. The complex role of implant surface topography and impact on healing response plays a role in biological criteria that can guide the design and development of future tissue-implant surface interfaces.
摘要
骨适应或植入物的整合以一系列生物反应为特征，这些反应始于界面处的骨转换（局部坏死过程），随后迅速修复。伤口愈合反应由巨噬细胞的复杂激活来引导，导致组织转换和植入物表面上新的成骨细胞分化。植入物表面形貌的复杂作用及其对愈合反应的影响在生物标准中发挥作用，这些标准可以指导未来组织-植入物表面界面的设计和开发。
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本文引用的文献
1
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J Biomed Mater Res A. 2010 May;93(2):724-37. doi: 10.1002/jbm.a.32587.
2
Nanostructured alumina-coated implant surface: effect on osteoblast-related gene expression and bone-to-implant contact in vivo.纳米结构氧化铝涂层种植体表面：对体内成骨细胞相关基因表达及骨与种植体接触的影响
Int J Oral Maxillofac Implants. 2009 Mar-Apr;24(2):205-15.
3
The effects of implant surface nanoscale features on osteoblast-specific gene expression.植入物表面纳米级特征对成骨细胞特异性基因表达的影响。
Biomaterials. 2009 Sep;30(25):4053-62. doi: 10.1016/j.biomaterials.2009.04.010. Epub 2009 May 21.
4
Surface nanofeature effects on titanium-adherent human mesenchymal stem cells.表面纳米特征对钛附着人间充质干细胞的影响。
Int J Oral Maxillofac Implants. 2009 Jan-Feb;24(1):38-46.
5
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6
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