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肯尼亚东部省份草药医生所使用的一些药用植物的抗菌活性。

Antimicrobial activity of some medicinal plants used by herbalists in Eastern province, Kenya.

作者信息

Kareru P G, Gachanja A N, Keriko J M, Kenji G M

机构信息

Department of Chemistry, Jomo Kenyatta University of Agriculture and Technology, P.O. BOX 62000-00200, Nairobi, Kenya.

出版信息

Afr J Tradit Complement Altern Med. 2007 Oct 27;5(1):51-5. doi: 10.4314/ajtcam.v5i1.31256.

Abstract

The aqueous extracts from medicinal plants commonly used by herbalists in Mbeere, and Embu districts of Eastern province, Kenya, were tested for their inhibitory activity against three selected strains of bacteria. All the selected plant extracts (infusions: 1.0 g sample in 100 ml water) investigated showed activity against Escherichia coli with inhibition zone diameters ranging from 5.8-18.0 mm. Terminalia brownii gave the largest inhibition zones against E. coli and Staphylococcus aureus. Vernonia lasiopus and Tithonia diversifolia were inactive to S. aureus and Bacillus subtilis, respectively. Eighteen and sixteen plants showed sensitivity of greater than 10 mm against S. aureus and B. subtilis, respectively. All control discs gave zones of inhibition of 12-24 mm, which were larger than those of the extracts. The present study validated the use of the selected medicinal plants by the herbalists in the treatment of bacterial ailments caused by the strains of bacteria investigated. Medicinal plants used for non-bacterial diseases also exhibited sensitivity towards bacterial strains tested. This implied they could be used as multi-purpose medicinal plants.

摘要

对肯尼亚东部省姆贝雷区和恩布区草药医生常用的药用植物水提取物进行了测试,以检测其对三种选定细菌菌株的抑制活性。所有研究的选定植物提取物(浸剂:1.0克样品溶于100毫升水中)均显示出对大肠杆菌的活性,抑菌圈直径范围为5.8 - 18.0毫米。布朗榄仁对大肠杆菌和金黄色葡萄球菌的抑菌圈最大。糙毛斑鸠菊和肿柄菊分别对金黄色葡萄球菌和枯草芽孢杆菌无活性。分别有18种和16种植物对金黄色葡萄球菌和枯草芽孢杆菌的敏感性大于10毫米。所有对照圆盘的抑菌圈为12 - 24毫米,大于提取物的抑菌圈。本研究证实了草药医生使用选定的药用植物治疗由所研究的细菌菌株引起的细菌性疾病的做法。用于非细菌性疾病的药用植物对所测试的细菌菌株也表现出敏感性。这意味着它们可以用作多用途药用植物。

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