利用超灵敏射频传感器区分单个酵母细胞的活力。
Distinguishing the viability of a single yeast cell with an ultra-sensitive radio frequency sensor.
机构信息
Department of Electrical and Computer Engineering, Clemson University, Clemson, South Carolina 29634, USA.
出版信息
Lab Chip. 2010 Mar 7;10(5):553-5. doi: 10.1039/b921502f. Epub 2010 Jan 26.
DOI:10.1039/b921502f
PMID:20162228
Abstract
We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (approximately 5.83 +/- 0.85 microm in diameter) are measured with clear sensing and identification of these cells.
摘要
我们提出并演示了一种简单、超灵敏的射频（RF）传感器，用于在微流道中检测单个酵母细胞并区分其活力。采用片上干扰来消除背景探测信号，以提高传感器的灵敏度。通过清晰的感应和识别，可以测量单个存活和非存活的酵母细胞（直径约为 5.83 ± 0.85 微米）。
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