Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Pediatr Blood Cancer. 2010 Jul 1;54(7):1041-4. doi: 10.1002/pbc.22437.
We describe a male with a large abdominal mass, most likely originating from the liver, with capsule rupture and tumor dissemination into the abdominal cavity. Adherence of the tumor to the diaphragm and lower right colon also were noted. A comprehensive evaluation of the mass revealed no tumor-defining histopathologic, immunocytochemical, ultrastructural, cytogenetic, or translocation features. The malignant tumor was found to have a novel translocation (X;19)(q13;13.3), which has not been reported in small round cell tumors of childhood or adults. The final diagnosis rendered was an undifferentiated small round cell tumor of uncertain cell of origin.
我们描述了一名男性患者，其腹部有一个巨大肿块，很可能源自肝脏，伴有包膜破裂和肿瘤播散至腹腔。还注意到肿瘤与膈肌和右下结肠粘连。对肿块进行的全面评估未发现肿瘤具有明确的组织病理学、免疫细胞化学、超微结构、细胞遗传学或易位特征。发现恶性肿瘤具有一种新的易位（X; 19）（q13; 13.3），这在儿童或成人的小圆细胞肿瘤中尚未报道过。最终诊断为未分化小圆细胞肿瘤，其起源细胞不确定。
