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坏死梭杆菌感染继发的勒米尔综合征,肝脓肿的罕见病因。

Lemierre's syndrome secondary to Fusobacterium necrophorum infection, a rare cause of hepatic abscess.

作者信息

Thoufeeq Muhammed Hameed, Salloum Waleed, Win Su Su, Sinha Leena

机构信息

Hull Royal Infirmary, Hull, United Kingdom.

出版信息

Acta Gastroenterol Belg. 2009 Oct-Dec;72(4):444-6.

Abstract

An 18-year-old male was admitted to the Accident & Emergency department with complaints of abdominal pain, vomiting and diarrhoea. He was clinically jaundiced and further CT scan suggested liver abscess. Later on blood cultures showed gram-negative bacilli and a further liver aspirate culture confirmed the presence of the rare Fusobacterium necrophorum. A diagnosis of hepatic abscess secondary to Lemierre's syndrome was made and patient was treated with appropriate antibiotics. Lemierre's syndrome, although a rare condition, may be associated with serious life-threatening complications. Early recognition and treatment is essential in successfully treating this rare condition. A review of Lemierre's syndrome is presented. We recommend clinicians to be aware of this condition (Lemierre's Syndrome) especially when dealing with young patients with sore throat and jaundice. It is important for primary care physicians to be aware of this condition as they are discouraged from prescribing antibiotics for young patients with sore throat. Although it is a rare condition, it is associated with severe life threatening complication like liver abscesses.

摘要

一名18岁男性因腹痛、呕吐和腹泻被送往急诊部。他临床上出现黄疸,进一步的CT扫描显示肝脓肿。后来血培养显示革兰氏阴性杆菌,进一步的肝穿刺抽吸培养证实存在罕见的坏死梭杆菌。诊断为继发于勒米尔综合征的肝脓肿,患者接受了适当的抗生素治疗。勒米尔综合征虽然罕见,但可能伴有严重的危及生命的并发症。早期识别和治疗对于成功治疗这种罕见疾病至关重要。本文对勒米尔综合征进行了综述。我们建议临床医生了解这种疾病(勒米尔综合征),尤其是在处理患有咽痛和黄疸的年轻患者时。初级保健医生了解这种疾病很重要,因为不鼓励他们为患有咽痛的年轻患者开抗生素。虽然这是一种罕见疾病,但它与肝脓肿等严重的危及生命的并发症有关。

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