Human Exposure and Atmospheric Sciences Division, National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.
Environ Sci Technol. 2010 Apr 1;44(7):2549-54. doi: 10.1021/es903777s.
In response to growing interest in human exposure to perfluorinated compounds (PFCs), the state of Minnesota measured and reported PFC concentrations in fish collected from the Minneapolis-St. Paul area. To better determine the geographical distribution of PFC contamination throughout Minnesota, fish were collected from 59 lakes throughout the state and several areas along the Mississippi River. Composite fish samples were analyzed for 10 PFC analytes by solid-phase extraction (SPE) and liquid chromatography-tandem mass spectrometry (LC/MS/MS). PFOS (perfluorooctanesulfonate) was the most commonly detected PFC, occurring in 73% of fish from the Mississippi River but only 22% of fish from lakes. Fish from Mississippi River Pool 2 near the Minneapolis-St. Paul area had the highest levels of PFOS, whereas locations upstream had PFOS concentrations below 40 ng/g, the concentration at which Minnesota issues "one meal per week" fish consumption advice. Fish from most Minnesota lakes tested (88%) had PFOS concentrations below 3 ng/g. Two lakes, McCarrons and Zumbro, contained fish with PFOS levels above 40 ng/g. The results reported here will help researchers to better understand the extent of PFC contamination in Minnesota fish and evaluate potential sources of contamination and will provide a basis for comprehensive fish consumption advice.
为了回应人们对人类接触全氟化合物（PFCs）日益增长的兴趣，明尼苏达州测量并报告了从明尼阿波利斯-圣保罗地区采集的鱼类中的 PFC 浓度。为了更好地确定明尼苏达州 PFC 污染的地理分布，从全州的 59 个湖泊和密西西比河沿岸的几个地区采集了鱼类样本。通过固相萃取（SPE）和液相色谱-串联质谱（LC/MS/MS）对 10 种 PFC 分析物进行了复合鱼类样本分析。全氟辛烷磺酸（PFOS）是最常见的 PFC，在密西西比河的 73%的鱼类中存在，但在湖泊鱼类中仅占 22%。明尼阿波利斯-圣保罗地区附近密西西比河 2 号池的鱼类中 PFOS 含量最高，而上游的 PFOS 浓度低于 40ng/g，这是明尼苏达州发布“每周食用一次”鱼类消费建议的浓度。大多数明尼苏达州湖泊中的鱼类样本（88%）的 PFOS 浓度低于 3ng/g。两个湖泊 McCarrons 和 Zumbro 的鱼类中 PFOS 含量超过 40ng/g。这里报告的结果将帮助研究人员更好地了解明尼苏达州鱼类中 PFC 污染的程度，并评估潜在的污染来源，并为全面的鱼类消费建议提供依据。
