Kiniş Vefa, Naiboğlu Bariş, Habeşoğlu Tülay Erden, Toros Sema Zer, Eriman Murat, Habeşoğlu Mehmet, Egeli Erol
Department of Otolaryngology, Haydarpaşa Training and Research Hospital, Istanbul, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2010 Jan-Feb;20(1):1-6.
The purpose of this study is to investigate the accuracy rates of tumor T-staging and the efficacy of methods used at T-staging.
Forty-seven laryngeal carcinoma patients (6 females, 41 males; mean age 57.9+/-9.8 years; range 38 to 81 years) who underwent surgery at Haydarpaşa Numune Education and Research Hospital 2nd Ear Nose Throat Clinic between March 2003 and June 2008 were included in the study. T-staging of the tumors were separately determined according to their clinical examination, computed tomography (CT) findings, and their correlation between these methods. Staging according to histopathological examination was accepted as real accurate staging. Rates of accurate staging according to postoperative histopathological examination results were evaluated under guidance of the literature.
When their accuracy rates in determining histopathological T-stages of tumors were compared, there were no significant differences between the methods. The rates of accuracy in determining histopathologic T-stage of tumors were 40% by clinical examination; 66% by CT; and 76% when both methods were used together. The most successful results were obtained at the tumors of glottic region. Among the patients whose tumors had been staged inaccurately by clinical examination, 71% were underestimated while 29% were overestimated. Underestimation and overestimation of stagings were found to be 37% and 63%, respectively, with CT examination.
Success of staging increases when clinical examination is used in together with CT. While there is a tendency towards underestimation of T-stage when staging is done only by means of clinical examination, this tendency is towards overestimation when CT is used alone. Thus, combination of clinical examination findings with CT is necessary for an accurate T-staging of a laryngeal cancer.
本研究旨在探讨肿瘤T分期的准确率以及T分期所采用方法的有效性。
纳入2003年3月至2008年6月期间在海达尔帕夏努姆内教育与研究医院第二耳鼻喉科诊所接受手术的47例喉癌患者(6例女性,41例男性;平均年龄57.9±9.8岁;年龄范围38至81岁)。根据临床检查、计算机断层扫描(CT)结果以及这些方法之间的相关性分别确定肿瘤的T分期。将根据组织病理学检查进行的分期视为真正准确的分期。在文献指导下评估根据术后组织病理学检查结果的准确分期率。
比较各方法在确定肿瘤组织病理学T分期时的准确率,各方法之间无显著差异。通过临床检查确定肿瘤组织病理学T分期的准确率为40%;通过CT为66%;两种方法联合使用时为76%。声门区肿瘤取得的结果最为成功。在临床检查对肿瘤分期不准确的患者中,71%被低估,29%被高估。CT检查发现分期低估和高估分别为37%和63%。
临床检查与CT联合使用时分期的成功率会提高。仅通过临床检查进行分期时存在T分期低估的趋势,而单独使用CT时则倾向于高估。因此,临床检查结果与CT相结合对于喉癌准确的T分期是必要的。