波士顿眼表面修复体用于治疗结膜黑色素瘤后持续的眼表上皮病变。
Boston Ocular Surface Prosthesis for persistent epitheliopathy after treatment of conjunctival melanoma.
机构信息
Harvard Medical School, Boston, MA, USA.
出版信息
Cornea. 2010 Apr;29(4):459-61. doi: 10.1097/ICO.0b013e3181b55b40.
PURPOSE
To report two cases of persistent epitheliopathy after treatment of conjunctival melanoma and review management options for this condition.
METHODS
Case report and literature review.
RESULTS
Persistent epitheliopathy, presumably resulting from limbal stem cell deficiency, is an uncommon complication of treatment of conjunctival malignant melanoma with surgical excision, cryotherapy, and mitomycin C. The Boston Ocular Surface Prosthesis was successful in improving vision, comfort, and epithelial status in our patients.
CONCLUSION
Persistent epitheliopathy is a rare complication of treatment of conjunctival melanoma. The Boston Ocular Surface Prosthesis is a viable treatment option in this situation.
目的
报告 2 例结膜黑色素瘤治疗后持续性上皮病，并复习该疾病的治疗选择。
方法
病例报告和文献复习。
结果
持续性上皮病，推测是由于角膜缘干细胞缺乏引起的，是手术切除、冷冻治疗和丝裂霉素 C 治疗结膜恶性黑色素瘤的一种罕见并发症。波士顿眼表面修复体成功改善了我们患者的视力、舒适度和上皮状态。
结论
持续性上皮病是结膜黑色素瘤治疗的罕见并发症。在这种情况下，波士顿眼表面修复体是一种可行的治疗选择。
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