[结膜黑色素瘤的治疗]
[Treatment of conjunctival melanoma].
作者信息
Salazar Méndez R, Baamonde Arbaiza B, de la Roz Martín P, Parra Rodríguez T
机构信息
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España.
Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Principado de Asturias, España.
出版信息
Arch Soc Esp Oftalmol. 2014 Feb;89(2):82-4. doi: 10.1016/j.oftal.2012.07.022. Epub 2012 Oct 10.
CLINICAL CASE
The cases of an 86 year-old woman and a 61 year-old man with conjunctival pigmented tumors are presented. An excisional biopsy, conjunctival cryotherapy and amniotic membrane grafts were performed in both cases, along with the application of mitomycin-C in the postoperative period. The histology study confirmed the clinical suspicion of melanoma. Tolerance was good during the follow-up with no signs of recurrence in the last 12 and 6 months, respectively.
DISCUSSION
The recommended treatment for conjunctival melanoma is surgical removal with adjunctive therapies such as cryotherapy or topical mitomycin-C. This is a well tolerated therapy and effective for preventing recurrences in the short-medium term.
临床病例
报告了一名86岁女性和一名61岁男性患有结膜色素性肿瘤的病例。两例均进行了切除活检、结膜冷冻治疗和羊膜移植，并在术后应用丝裂霉素C。组织学研究证实了临床对黑色素瘤的怀疑。随访期间耐受性良好，分别在过去12个月和6个月内无复发迹象。
讨论
结膜黑色素瘤的推荐治疗方法是手术切除并辅以冷冻治疗或局部应用丝裂霉素C等疗法。这是一种耐受性良好的治疗方法，对预防中短期复发有效。
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