Kherad Omar, Rutschmann O T
Département de médecine interne, Hôpitaux Universitaires de Genève et Faculté de médecine de Genève.
Praxis (Bern 1994). 2010 Feb 17;99(4):235-40. doi: 10.1024/1661-8157/a000034.
COPD is a progressive disease whom course is characterized by repeated exacerbations, with a negative impact on quality of life and health costs. Although a causal link between the identification of viruses in the upper respiratory tract and exacerbation is not definitively established, there is growing evidence that viruses are important triggers of exacerbations in more than 50 percent of cases. Yet, neither clinical presentation nor biological markers permit to discriminate between viral and non viral exacerbations.
慢性阻塞性肺疾病(COPD)是一种进行性疾病,其病程的特点是反复加重,对生活质量和医疗费用产生负面影响。虽然上呼吸道病毒检测与病情加重之间的因果关系尚未明确确立,但越来越多的证据表明,在超过50%的病例中,病毒是病情加重的重要触发因素。然而,无论是临床表现还是生物学标志物都无法区分病毒感染导致的加重和非病毒感染导致的加重。