Müller Markus K, Nocito A, Schiesser M
Klinik für Viszeral- und Transplantationschirurgie, Universitätsspital Zürich, Zürich.
Praxis (Bern 1994). 2010 Feb 17;99(4):241-7. doi: 10.1024/1661-8157/a000035.
Diabetes mellitus type 2 is a chronic disease with increasing prevalence in western society. Obesity represents a well established risk factor for the development of diabetes mellitus type 2. Several studies on surgical procedures for the treatment of obesity have shown a postoperative reduction of obesity-related co-morbidities. Thus, diabetes mellitus type 2 was shown to resolve or improve in more than 75% of morbidly obese patients (BMI >35) after bariatric surgery. These insights paved the way for the advent of metabolic surgery - a novel field with the goal to improve glucose metabolism in patients with a BMI of less than 35. Encouraging results from mostly observational studies have sparked the interest in the surgical management of diabetes mellitus type 2.
2型糖尿病是一种在西方社会中患病率不断上升的慢性疾病。肥胖是2型糖尿病发生的一个公认风险因素。多项关于肥胖治疗手术的研究表明，术后肥胖相关合并症有所减少。因此，在减重手术后，超过75%的病态肥胖患者（体重指数>35）的2型糖尿病得到缓解或改善。这些见解为代谢手术的出现铺平了道路，代谢手术是一个新领域，目标是改善体重指数低于35的患者的葡萄糖代谢。大多来自观察性研究的鼓舞人心的结果引发了人们对2型糖尿病手术治疗的兴趣。
