Laboratoire de Chimie, CNRS, Ecole Normale Supeéieure de Lyon, F-69364 Lyon 07, France.
J Org Chem. 2010 Mar 19;75(6):2099-102. doi: 10.1021/jo100052r.
The first hemicryptophanes derived from tris(N-alkyl-carbamoylmethyl)amine and tris(2-aminoethyl)amine (tren) have been synthesized following a single synthetic pathway that allows the subsequent formation of the two heteroditopic hosts 3 and 4. X-ray crystal structures show a well-defined cavity encapsulating a solvent guest for both compounds emphasizing their complexation properties.
首次合成了源自三（N-烷基氨甲酰甲基）胺和三（2-氨基乙基）胺（tren）的半笼状化合物，采用单一合成途径，随后形成了两个杂双位主体 3 和 4。X 射线晶体结构显示了一个明确的空腔，可容纳两种化合物的溶剂客体，强调了它们的配位性质。
