一般成年人群标准静息心电图中 R 波递增不良的患病率及其预后价值。健康 2000 调查。

Prevalence and prognostic value of poor R-wave progression in standard resting electrocardiogram in a general adult population. The Health 2000 Survey.

机构信息

Division of Internal Medicine, Department of Cardiology, Seinäjoki Central Hospital, Finland.

出版信息

Ann Med. 2010 Mar;42(2):123-30. doi: 10.3109/07853890903555334.

DOI:10.3109/07853890903555334

PMID:20166814

Abstract

AIMS

We examined the prevalence and prognostic impact of poor R-wave progression (PRWP) in a standard electrocardiogram (ECG) in a general population.

METHODS

Data and standard resting ECG recording were collected from a large nationally representative (random sample) health examination survey conducted in Finland in 2000-2001. The final study population consisted of 5613 individuals.

RESULTS

The prevalence of PRWP (defined as RV3 < or = 3 mm and RV2 < or = RV3) was 7.0% in women and 2.7% in men (P< or = 0.001 for difference). During follow-up of 70 +/- 9 months (mean +/- SD), 317 patients died (5.6%). Both all-cause and cardiovascular mortality was higher in the group with PRWP than in those without PRWP in both women and men. In Cox regression analysis after adjustment for age, hypertension, diabetes, previous myocardial infarction, and coronary heart disease, the relative risk for all-cause mortality for PRWP was 1.69 (95% CI 0.89-3.22, P=0.112) for men and 2.00 (95% CI 1.28-3.13, P=0.002) for women. For cardiovascular mortality the relative risk for individuals with PRWP was 1.85 (0.74-4.65, P=0.19) for men and 3.02 (1.54-5.93, P=0.001) for women.

CONCLUSIONS

PRWP is a common ECG finding and predicts risk for total and cardiovascular mortality in women in a general population.

摘要

目的

我们在一般人群中检查了标准心电图（ECG）中 R 波进展不良（PRWP）的患病率和预后影响。

方法

数据和标准静息 ECG 记录来自于 2000-2001 年在芬兰进行的一项大型全国代表性（随机抽样）健康检查调查。最终研究人群由 5613 名个体组成。

结果

PRWP（定义为 RV3 <= 3 毫米和 RV2 <= RV3）的患病率在女性中为 7.0%，在男性中为 2.7%（女性与男性差异<0.001）。在 70 +/- 9 个月（平均值 +/- SD）的随访期间，有 317 名患者死亡（5.6%）。在女性和男性中，无论是否存在 PRWP，全因和心血管死亡率均在 PRWP 组中更高。在调整年龄、高血压、糖尿病、既往心肌梗死和冠心病后，Cox 回归分析显示，PRWP 与全因死亡率的相对风险在男性为 1.69（95%CI 0.89-3.22，P=0.112），在女性为 2.00（95%CI 1.28-3.13，P=0.002）。对于心血管死亡率，PRWP 患者的相对风险在男性为 1.85（95%CI 0.74-4.65，P=0.19），在女性为 3.02（95%CI 1.54-5.93，P=0.001）。