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[结肠低分化内分泌癌]

[Poorly differentiated endocrine carcinoma of the colon].

作者信息

Saint-Blancard P, Hervouet M, Chapuis O

机构信息

Service d'anatomie et de cytologie pathologiques, hôpital d'Instruction des Armées Percy, 101, avenue Henri-Barbusse, 92141 Clamart cedex, France.

出版信息

Rev Med Interne. 2010 Jun;31(6):e10-2. doi: 10.1016/j.revmed.2009.03.368. Epub 2010 Feb 18.

Abstract

Small-cell endocrine carcinoma is a particularly aggressive form of endocrine carcinoma characterized by its rapid and early metastatic dissemination. We report a 59-year-old man who presented with abdominal pain as the initial manifestation of a colonic small-cell endocrine carcinoma with early liver metastases and poor prognosis. Poorly differentiated endocrine carcinomas are rare tumours that generally occur in the lung, but are exceptionally localized in other sites. Generally, these tumours have an aggressive behaviour with early metastatic spread, and curative surgical resection is often impossible. Despite aggressive chemotherapy, these extended tumours have an unfavourable outcome.

摘要

小细胞内分泌癌是一种侵袭性特别强的内分泌癌,其特点是转移迅速且早期广泛扩散。我们报告一名59岁男性,他以腹痛为首发表现,诊断为结肠小细胞内分泌癌伴早期肝转移,预后不良。低分化内分泌癌是罕见肿瘤,通常发生于肺部,但也有罕见地发生于其他部位的情况。一般来说,这些肿瘤具有侵袭性行为,早期即发生转移扩散,常常无法进行根治性手术切除。尽管进行了积极化疗,这些进展期肿瘤的预后仍不佳。

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