Bakhshi Sameer, Meel Rachna, Mohanti Bidhu Kalyan, Hasan Naqvi Syed Ghaffar
Department of Medical, All India Institute of Medical Sciences, New Delhi, India.
J Pediatr Hematol Oncol. 2010 Mar;32(2):e42-5. doi: 10.1097/MPH.0b013e3181bfcd83.
Nonmetastatic extraocular retinoblastoma is a common entity in South-East Asia. We did a retrospective study of patients treated for isolated extraocular retinoblastoma, that is, International retinoblastoma staging system stages II and III, using a uniform chemotherapy protocol at our oncology center, between June 2003 and June 2008. Out of the 25 patients having nonmetastatic extraocular retinoblastoma, 6 were in stage II, and 19 in stage III. The probability of event-free survival was 0.54 at 18 months of follow-up with no significant difference between the 2 stages and the presence of optic nerve involvement; 11 out of 13 relapses were systemic. This is the largest case series of nonmetastatic extraocular retinoblastoma from South-East Asia.
非转移性眼外视网膜母细胞瘤在东南亚是一种常见病症。我们对2003年6月至2008年6月期间在我们肿瘤中心接受孤立性眼外视网膜母细胞瘤治疗（即国际视网膜母细胞瘤分期系统II期和III期）的患者进行了一项回顾性研究。在25例非转移性眼外视网膜母细胞瘤患者中，6例为II期，19例为III期。随访18个月时无事件生存率为0.54，两个分期之间以及视神经受累情况之间无显著差异；13例复发中有11例为全身性复发。这是来自东南亚的最大规模非转移性眼外视网膜母细胞瘤病例系列。
