Ullmann D, Phillips R L, Beeson W L, Dewey H G, Brin B N, Kuzma J W, Mathews C P, Hirst A E
Department of Preventive Medicine, School of Medicine, Oregon Health Sciences University, Portland 97201-3098.
JAMA. 1991 May 8;265(18):2352-9.
We compare the mortality experience of medical school graduates from Loma Linda University (LLU [n = 4342]) and the University of Southern California (USC [n = 2832]) with each other and with that of contemporaneous, white, American men. When compared with US white men from the general population, both USC and LLU graduates had below expected deaths for all causes (USC, standardized mortality ratio [SMR] = 76; LLU, SMR = 56), although deaths due to cerebrovascular disease, airplane accidents, and suicides were elevated for USC (SMRs = 132, 360, and 218, respectively). The LLU graduates had a risk similar to that of the USC graduates for fatal cancer, with a mortality ratio (MR) of 0.92 (95% confidence interval, 0.67 to 1.26); but half the risk of fatal atherosclerotic disease, with MRs of 0.58 (0.46 to 0.73) and 0.66 (0.43 to 0.99) for coronary and cerebrovascular disease, respectively; and three times the risk of fatal airplane accidents. The overall mortality rate of LLU physicians was only 75% as high as that of the USC physicians and only 56% as high as that of the US male population at large. We attribute this reduced mortality mainly to the low cardiovascular mortality rates, which may be accounted for by the life-style of the substantial proportion of Seventh-day Adventists among LLU graduates.
我们将洛马林达大学(LLU [n = 4342])和南加州大学(USC [n = 2832])医学院毕业生的死亡情况相互比较,并与同时期的美国白人男性进行比较。与普通人群中的美国白人男性相比,南加州大学和洛马林达大学的毕业生各类死因的死亡人数均低于预期(南加州大学,标准化死亡率[SMR] = 76;洛马林达大学,SMR = 56),不过南加州大学因脑血管疾病、飞机事故和自杀导致的死亡人数有所增加(SMR分别为132、360和218)。洛马林达大学毕业生患致命癌症的风险与南加州大学毕业生相似,死亡率(MR)为0.92(95%置信区间为0.67至1.26);但患致命动脉粥样硬化疾病的风险只有南加州大学毕业生的一半,冠心病和脑血管疾病的MR分别为0.58(0.46至0.73)和0.66(0.43至0.99);而死于飞机事故的风险是南加州大学毕业生的三倍。洛马林达大学医生的总体死亡率仅为南加州大学医生的75%,仅为美国男性总体死亡率的56%。我们将这种死亡率降低主要归因于心血管疾病死亡率较低,这可能是由于洛马林达大学毕业生中有相当比例的基督复临安息日会信徒的生活方式所致。