腺病毒感染致回盲部肠套叠伴炎症性神经病组织形态学特征。
Ileocecal intussusception with histomorphological features of inflammatory neuropathy in adenovirus infection.
机构信息
Department of Pediatrics, RWTH Aachen University, 52074 Aachen, Germany.
出版信息
Gastroenterol Res Pract. 2009;2009:579501. doi: 10.1155/2009/579501. Epub 2010 Feb 11.
Abstract
The pathophysiological mechanisms for ileocecal intussusception in children with adenovirus infection are not well characterized. Here we demonstrate coincidence of adenovirus infection and inflammatory neuropathy of myenteric plexus in two children with ileocecal intussusception. Inflammatory neuropathy, an unspecific morphological feature which is found in peristalsis disorders, was morphologically characterized by the influx of CD3 positive lymphocytes in nervous plexus. To our knowledge, this is the first report suggesting peristalsis disorders from inflammatory neuropathy as additional mechanism in the pathophysiological concept of adenovirus-associated ileocecal intussusception.
摘要
腺病毒感染致回盲肠套叠的病理生理机制尚不清楚。本研究在 2 例回盲肠套叠患儿中发现腺病毒感染与肌间神经丛炎症性神经病同时存在。炎症性神经病是一种非特异性形态学特征，存在于蠕动障碍中，其形态学特征为 CD3 阳性淋巴细胞浸润神经丛。据我们所知，这是首例提示炎症性神经病导致蠕动障碍的报道，这为腺病毒相关性回盲肠套叠的病理生理概念提供了额外的机制。
相似文献
1
Ileocecal intussusception with histomorphological features of inflammatory neuropathy in adenovirus infection.
Gastroenterol Res Pract. 2009;2009:579501. doi: 10.1155/2009/579501. Epub 2010 Feb 11.
2
New hypothesis on the pathogenesis of ileocecal intussusception.
J Pediatr Surg. 2007 Sep;42(9):1515-9. doi: 10.1016/j.jpedsurg.2007.04.025.
3
[Ileocaecal intussusception associated with adenovirus infection: a case report].
Infez Med. 2010 Dec;18(4):256-8.
4
Adenovirus and ileocecal intussusception.
Lab Invest. 1975 Oct;33(4):347-51.
5
Ileocecal intussusception of small-bowel lymphoma: diagnosis by colonoscopy.
J Clin Gastroenterol. 1997 Jul;25(1):358-61. doi: 10.1097/00004836-199707000-00014.
6
Intussusception, adenovirus, and children: a brief reaffirmation.
Hum Pathol. 1994 Feb;25(2):169-74. doi: 10.1016/0046-8177(94)90274-7.
7
Adenovirus infection and childhood intussusception.
Am J Dis Child. 1992 Nov;146(11):1331-3. doi: 10.1001/archpedi.1992.02160230089026.
8
Ileocecal-colonic intussusception caused by cecal adenocarcinoma A case report.
Ann Ital Chir. 2012 Sep 12;2012:S2239253X12019081.
9
Stool filling of an intestinal duplication cyst at the ileocecal valve triggers colonic intussusception: a case report.
Surg Case Rep. 2018 Sep 15;4(1):116. doi: 10.1186/s40792-018-0527-z.
10
Ileocecal intussusception in horses: 26 cases (1981-1988).
J Am Vet Med Assoc. 1990 Jan 1;196(1):121-6.
引用本文的文献
1
Nomogram for spontaneous reduction in pediatric intussusception: a retrospective study.
Front Pediatr. 2025 Jul 9;13:1571203. doi: 10.3389/fped.2025.1571203. eCollection 2025.
2
Epidemiology, clinical characteristics, and treatment of children with acute intussusception: a case series.
BMC Pediatr. 2023 Mar 30;23(1):143. doi: 10.1186/s12887-023-03961-y.
3
Ileocolic intussusception in pediatric SARS-CoV-2 patients: experience at a tertiary pediatric center.
Pediatr Surg Int. 2022 Mar;38(3):437-443. doi: 10.1007/s00383-022-05061-x. Epub 2022 Jan 8.
4
Systemic lupus erythematous as an unusual cause of intussusception in Sudanese woman: A case report.
Clin Case Rep. 2021 Oct 8;9(10):e04939. doi: 10.1002/ccr3.4939. eCollection 2021 Oct.
5
Epidemiological Correlation between Fecal Adenovirus Subgroups and Pediatric Intussusception in Korea.
J Korean Med Sci. 2017 Oct;32(10):1647-1656. doi: 10.3346/jkms.2017.32.10.1647.
6
Clinical features and role of viral isolates from stool samples of intussuception in children.
Pediatr Gastroenterol Hepatol Nutr. 2013 Sep;16(3):162-70. doi: 10.5223/pghn.2013.16.3.162. Epub 2013 Sep 30.
本文引用的文献
1
Clinical features and long-term survival in chronic intestinal pseudo-obstruction and enteric dysmotility.
Scand J Gastroenterol. 2009;44(6):692-9. doi: 10.1080/00365520902839642.
2
Full-thickness biopsy findings in chronic intestinal pseudo-obstruction and enteric dysmotility.
Gut. 2009 Aug;58(8):1084-90. doi: 10.1136/gut.2008.148296. Epub 2009 Jan 9.
3
Paediatric intussusception: epidemiology and outcome.
Emerg Med Australas. 2007 Feb;19(1):45-50. doi: 10.1111/j.1742-6723.2007.00923.x.
4
Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia.
J Clin Microbiol. 2006 Sep;44(9):3371-3. doi: 10.1128/JCM.01289-06.
5
Ileocecal intussusception in an adult: the laparoscopic approach.
JSLS. 2006 Apr-Jun;10(2):250-3.
6
Adenoviral disease in pediatric solid organ transplant recipients.
Pediatr Transplant. 2006 Feb;10(1):17-25. doi: 10.1111/j.1399-3046.2006.00427.x.
7
Intussusception among young children in Europe.
Pediatr Infect Dis J. 2006 Jan;25(1 Suppl):S22-9. doi: 10.1097/01.inf.0000197713.32880.46.
8
A review of viral gastroenteritis.
Curr Opin Infect Dis. 2004 Oct;17(5):461-9. doi: 10.1097/00001432-200410000-00011.
9
Twenty-one cases of small bowel intussusception: the pathophysiology of idiopathic intussusception and the concept of benign small bowel intussusception.
Pediatr Surg Int. 2004 Feb;20(2):140-3. doi: 10.1007/s00383-003-1055-9. Epub 2004 Feb 10.
10
Childhood intussusception: a 9-year review.
Ann Trop Paediatr. 2000 Jun;20(2):131-5. doi: 10.1080/02724936.2000.11748122.
Zotero 插件