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[原发性静脉曲张的治疗]

[Treatment of primary varicosis].

作者信息

Noppeney T, Nüllen H

机构信息

MVZ Gefässmedizin Nürnberg, Nürnberg, Deutschland.

出版信息

Internist (Berl). 2010 Mar;51(3):344-50. doi: 10.1007/s00108-009-2515-7.

DOI:10.1007/s00108-009-2515-7
PMID:20169330
Abstract

While the treatment of varicose veins has remained unchanged over the past 100 years based on the three principles of compression, sclerotherapy, and classic varicose vein surgery, alternative approaches and advancements in treatment have developed in the last 10 years such as foam sclerotherapy, endovenous laser therapy, and radiofrequency obliteration. In contrast to classic varicose vein surgery, prospective, randomized, comparative studies are available with respect to the modern treatment procedures. They clearly show that endovenous thermal techniques are not inferior to the classic operation regarding the perioperative complication rate. There appears to be a tendency toward considerably fewer perioperative complaints with endovenous laser therapy and in particular with radiofrequency obliteration. Foam sclerotherapy represents a minimally invasive alternative that is markedly cost-effective. Even though the occlusion rate of the root veins after foam sclerotherapy is not as good as after endovenous therapy, the method is initially very effective. Especially in cases of recurrent varicose veins from the saphenofemoral or popliteal junction, foam sclerotherapy should be considered as the ideal method. All procedures significantly improve the patients' quality of life and the symptom complaints related to varicose veins. They are not in competition, but rather partially complement each other so that a combination of several approaches is quite judicious.

摘要

尽管在过去100年里,基于压迫、硬化疗法和经典静脉曲张手术这三个原则,静脉曲张的治疗方法一直没有改变,但在过去10年里,出现了一些替代方法和治疗进展,如泡沫硬化疗法、静脉内激光治疗和射频消融术。与经典静脉曲张手术不同,关于现代治疗方法有前瞻性、随机、对照研究。这些研究清楚地表明,就围手术期并发症发生率而言,静脉内热技术并不逊色于经典手术。静脉内激光治疗,尤其是射频消融术,似乎有明显减少围手术期不适的趋势。泡沫硬化疗法是一种微创替代方法,具有显著的成本效益。尽管泡沫硬化疗法后根部静脉的闭塞率不如静脉内治疗后好,但该方法起初非常有效。特别是在大隐静脉-股静脉或腘静脉交界处复发性静脉曲张的病例中,泡沫硬化疗法应被视为理想方法。所有治疗方法都能显著改善患者的生活质量以及与静脉曲张相关的症状。它们并非相互竞争,而是部分相互补充,因此几种方法联合使用是非常明智的。

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本文引用的文献

1
Endovenous laser treatment: a morphological study in an animal model.静脉内激光治疗:动物模型的形态学研究
Phlebology. 2009 Aug;24(4):166-75. doi: 10.1258/phleb.2009.008070.
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Radiofrequency endovenous ClosureFAST versus laser ablation for the treatment of great saphenous reflux: a multicenter, single-blinded, randomized study (RECOVERY study).
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Randomized clinical trial comparing endovenous laser with cryostripping for great saphenous varicose veins.比较大隐静脉曲张腔内激光治疗与冷冻剥脱术的随机临床试验。
Br J Surg. 2008 Oct;95(10):1232-8. doi: 10.1002/bjs.6351.
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Endovenous therapies of lower extremity varicosities: a meta-analysis.下肢静脉曲张的腔内治疗:一项荟萃分析
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Systematic review and meta-analysis of endovenous radiofrequency obliteration, endovenous laser therapy, and foam sclerotherapy for primary varicosis.原发性静脉曲张腔内射频消融、腔内激光治疗和泡沫硬化疗法的系统评价与荟萃分析
J Cardiovasc Surg (Torino). 2008 Apr;49(2):213-33.
6
Treatment of the incompetent great saphenous vein by endovenous radiofrequency powered segmental thermal ablation: first clinical experience.经皮腔内射频分段热消融治疗大隐静脉功能不全:首例临床经验
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Outcomes and side effects of duplex-guided sclerotherapy in the treatment of great saphenous veins with 1% versus 3% polidocanol foam: results of a randomized controlled trial with 1-year follow-up.
Dermatol Surg. 2007 Mar;33(3):276-81. doi: 10.1111/j.1524-4725.2007.33062.x.
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Outcome of ultrasound-guided sclerotherapy for varicose veins: medium-term results assessed by ultrasound surveillance.
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Investigation on radiofrequency and laser (980 nm) effects after endoluminal treatment of saphenous vein insufficiency in an ex-vivo model.在体外模型中对隐静脉功能不全进行腔内治疗后射频和激光(980纳米)效应的研究。
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Long-term outcomes of endovenous radiofrequency obliteration of saphenous reflux as a treatment for superficial venous insufficiency.大隐静脉反流的静脉内射频消融术治疗下肢浅静脉功能不全的长期疗效
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