Department of Urology, The First Affiliated Hospital of Soochow University, 188 Shizi Street, 215006, Suzhou, Jiangsu, China.
Int Urol Nephrol. 2010 Dec;42(4):897-901. doi: 10.1007/s11255-010-9711-1. Epub 2010 Feb 19.
To investigate an appropriate treatment for patients with upper ureteral stones, > 15 mm in size, by comparing the therapeutic outcomes for those undergoing retroperitoneoscopic ureterolithotomy (RPUL) and rigid ureteroscopic pneumatic lithotripsy (URSPL) retrospectively.
During the study period, 81 patients with a large upper ureteral stone (> 15 mm) were divided into two groups. RPUL was performed with retroperitoneal approach, and the stone was removed in group A. URSPL was conducted using a rigid ureteroscope, and pneumatic probe was used for lithotripsy in group B. The patient characteristics, success rate, stone-free rate, operation time, and complications were analyzed prospectively in the two groups.
The success rates of operation were 94.5% (34/36) in group A and 88.8% (40/45) in group B, but there were no significant differences between two groups (P > 0.05). After 4 weeks of follow-up, the stone-free rate after RPUL (100%, 34/34) and URSPL (77.5%, 31/40) groups were statistically different (P = 0.006). Furthermore, simultaneous ureterolithotomy and ureteroplasty by retroperitoneal laparoscopic surgery were performed on four patients combined with ureteral stricture. However, the mean operation time and hospital staying time after surgery in group A were longer than that in group B, and the differences were statistically significant (P < 0.05). The complication rate after RPUL (17.6%, 6/34) was lower than that after URSPL (20%, 8/40), but the differences were not statistically significant (P > 0.05).
RPUL is a safe and effective treatment technique for large, impacted, upper ureteral stones >15 mm in size when first-line treatments have failed or are unlikely to be effective. It can handle with combined pathologies simultaneously.
通过回顾性比较经后腹腔镜输尿管切开取石术(RPUL)和硬性输尿管镜气压弹道碎石术(URSPL)治疗输尿管上段大结石(>15mm)的疗效,探讨一种合适的治疗方法。
研究期间,81 例输尿管上段大结石(>15mm)患者分为两组。A 组采用后腹腔镜入路行 RPUL,取出结石;B 组采用硬性输尿管镜行 URSPL,气压弹道探针碎石。前瞻性分析两组患者的一般资料、手术成功率、结石清除率、手术时间、并发症等。
A 组手术成功率为 94.5%(34/36),B 组为 88.8%(40/45),两组间差异无统计学意义(P>0.05)。4 周后随访,RPUL 组(100%,34/34)和 URSPL 组(77.5%,31/40)结石清除率差异有统计学意义(P=0.006)。另外,4 例合并输尿管狭窄患者同期行后腹腔镜输尿管切开取石和输尿管成形术。但 A 组手术时间和术后住院时间长于 B 组,差异有统计学意义(P<0.05)。RPUL 组并发症发生率(17.6%,6/34)低于 URSPL 组(20%,8/40),但差异无统计学意义(P>0.05)。
对于一线治疗无效或效果不佳的>15mm 输尿管上段大结石,RPUL 是一种安全有效的治疗方法,可同时处理合并症。