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布鲁氏菌病:急性髓系白血病发热性中性粒细胞减少症的罕见病因。

Brucellosis: a rare cause of febrile neutropenia in acute myeloblastic leukemia.

机构信息

Hematology Department, School of Medicine, Celal Bayar University, Manisa, Turkey.

出版信息

Med Oncol. 2011 Mar;28(1):255-7. doi: 10.1007/s12032-010-9440-4. Epub 2010 Feb 19.

Abstract

Brucellosis is a zoonotic disease and endemically seen in the Middle East, Eastern Europe and continental America. Febrile neutropenia related to Brucellosis has been reported only in a few cases. Brucella was cultured from the bone marrow of a 42-year-old woman who was admitted to hospital with symptoms of fever and fatigue and later diagnosed as acute myeloblastic leukemia (AML). The patient was treated for both AML and Brucellosis without any problems and discharged from the hospital after scheduling her follow-up visits. Brucellosis might be considered in the etiology of febrile neutropenia in endemic regions and must be treated effectively to prevent possible morbidity and mortality during or after chemotherapy.

摘要

布鲁氏菌病是一种人畜共患病,在地中海东部、东欧和美洲大陆流行。仅在少数情况下有报道称与布鲁氏菌病相关的发热性中性粒细胞减少症。从一名因发热和疲劳而住院的 42 岁女性的骨髓中培养出了布鲁氏菌,后来被诊断为急性髓细胞白血病(AML)。该患者在接受 AML 和布鲁氏菌病治疗时没有出现任何问题,并在安排好随访后出院。在流行地区,发热性中性粒细胞减少症的病因中应考虑布鲁氏菌病,并必须有效治疗,以预防化疗期间或之后可能出现的发病率和死亡率。

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