Malik G M
College of Medicine, King Saud University, Abha Branch, Saudi Arabia.
Am J Trop Med Hyg. 1997 Apr;56(4):375-7. doi: 10.4269/ajtmh.1997.56.375.
One hundred four Saudi patients with brucellosis who were admitted to Abha General Hospital in the Asir region of southern Saudi Arabia were studied. All the patients had Brucella melitensis infection; 61.5% were females while 38.5% were males. Their mean age was 32 years. Most of the patients (61.5%) lived in the lowland (Tihama) and the majority were shepherds (84.6%). The most common presenting symptoms were fever (100%), sweating (96.2%), headache (76.9%), joint pains (76.9%), and backache (73.1%). Physical findings included fever (96.2%), hepatomegaly (46.2%), splenomegaly (42.3%), tenderness over the spine (30.8%), arthritis (26.9%), and lymphadenopathy (19.2%). Mild anemia, leukopenia, and relative lymphocytosis were common. A history of raw milk ingestion was an important factor in disease transmission (84.6%), followed by close animal contact (73%) and raw liver consumption (63.3%). The study shows the effectiveness of several drug combinations in the treatment of brucellosis and the low relapse rate if the treatment is prolonged for not less than six weeks.
对沙特阿拉伯南部阿西尔地区阿巴哈综合医院收治的104例布鲁氏菌病患者进行了研究。所有患者均感染马尔他布鲁氏菌；61.5%为女性，38.5%为男性。他们的平均年龄为32岁。大多数患者（61.5%）生活在低地（蒂哈马），大多数是牧民（84.6%）。最常见的症状是发热（100%）、出汗（96.2%）、头痛（76.9%）、关节疼痛（76.9%）和背痛（73.1%）。体格检查发现包括发热（96.2%）、肝肿大（46.2%）、脾肿大（42.3%）、脊柱压痛（30.8%）、关节炎（26.9%）和淋巴结病（19.2%）。轻度贫血、白细胞减少和相对淋巴细胞增多很常见。饮用生牛奶史是疾病传播的一个重要因素（84.6%），其次是密切接触动物（73%）和食用生肝（63.3%）。该研究表明几种药物联合治疗布鲁氏菌病的有效性，以及如果治疗延长不少于六周则复发率较低。
