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激光热角膜成形术引起的角膜组织机械变形模拟:有限元方法研究

Simulation of corneal tissue mechanical deformation due to laser thermokeratoplasty: a finite element methods study.

作者信息

Yang Y F, Zhang J, Wang X H, Wang Q, Mei J, Zeng Y J

机构信息

Biomechanics & Medical Information Institute, Beijing University of Technology, Beijing 100022, China.

出版信息

Australas Phys Eng Sci Med. 2009 Dec;32(4):220-5. doi: 10.1007/BF03179242.

DOI:10.1007/BF03179242
PMID:20169841
Abstract

Laser thermokeratoplasty (LTK) is the ophthalmologic procedure used for the correction of hyperopia. In this paper, the grid compartmentalization, loading and restriction of cornea model were reported based on the principle and process of LTK. The corneal deformation and the change of curvature radius were analyzed with different operation parameters. The effects of different parameters on the corneal curvature were obtained and consequently the effects on the diopter correction were determined. It was found that eye pressure only had a small effect on the changes of cornea diopter. Under the same eye pressure, the greater the diameter of operation area changed, the greater the corneal curvature changed with a more obvious operation efficacy. To obtain a significant operation efficacy, the diameter of operation area should not be less than 4.5 mm.

摘要

激光热角膜成形术(LTK)是一种用于矫正远视的眼科手术。本文基于LTK的原理和过程,报道了角膜模型的网格划分、加载和约束。分析了不同手术参数下角膜的变形情况以及曲率半径的变化。得到了不同参数对角膜曲率的影响,进而确定了对屈光度矫正的影响。结果发现,眼压对角膜屈光度变化的影响较小。在相同眼压下,手术区域直径变化越大,角膜曲率变化越大,手术效果越明显。为获得显著的手术效果,手术区域直径不应小于4.5毫米。

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