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[睫状体中胚叶平滑肌瘤——病例报告]

[Mesectodermal leiomyoma of the ciliary body--case report].

作者信息

Sojka Paulina, Pogrzebielski Arkadiusz, Orłowska-Heitzman Jolanta, Romanowska-Dixon Bozena

机构信息

Ze Studenckiego Koła Naukowego przy Katedrze Patomorfologii Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie.

出版信息

Klin Oczna. 2009;111(10-12):350-3.

Abstract

PURPOSE

The aim of this report is to present a case of mesectodermal leiomyoma of the ciliary body.

MATERIAL AND METHODS

In the left eye of the 15 years old female patient presenting 2 months history of deterioration of visual acuity a medium-pigmented, dome-shaped tumor at the inferotemporal side was detected. It measured 21.6 mm in base diameter 11.2 mm in thickness and was revealed with imaging techniques such as ultrasound, MRI and orbital radiography. Taking into consideration all clinical features, despite patients' young age, malignant melanoma of the ciliary body was suspected. Due to the size of the tumor and the impossibility of conducting conservative treatment the globe was eventually enucleated.

RESULTS

The final diagnosis was established on the basis of histopathological microscopic examination and immunohistochemical stains. The co-expression of muscular (SMA, caldesmon, desmin), as well as neural markers (S-100 protein and synaptophysin), has been proved.

CONCLUSIONS

Mesectodermal leiomyoma of the ciliary body is an extremely rare benign tumor, which originates from neural crests. It exhibits features of both muscular and neural differentiation.

摘要

目的

本报告旨在介绍一例睫状体中外胚层平滑肌瘤病例。

材料与方法

在一名15岁女性患者的左眼,该患者有2个月视力下降病史,在颞下侧检测到一个中等色素沉着、圆顶状肿瘤。其基底直径为21.6毫米,厚度为11.2毫米,通过超声、MRI和眼眶放射ography等成像技术显示。考虑到所有临床特征,尽管患者年龄较小,但怀疑为睫状体恶性黑色素瘤。由于肿瘤大小以及无法进行保守治疗,最终摘除了眼球。

结果

最终诊断基于组织病理学显微镜检查和免疫组化染色确定。已证实肌肉(平滑肌肌动蛋白、钙调蛋白、结蛋白)以及神经标志物(S-100蛋白和突触素)的共表达。

结论

睫状体中外胚层平滑肌瘤是一种极其罕见的良性肿瘤,起源于神经嵴。它表现出肌肉和神经分化的特征。

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