[睫状体中胚叶平滑肌瘤——临床特征、手术及免疫组织化学]

[Mesectodermal leiomyoma of the ciliary body--clinical aspects, surgery and immunohistochemistry].

作者信息

Burk R O, Völcker H E, Daus W, Born I A

出版信息

Fortschr Ophthalmol. 1989;86(6):631-5.

Abstract

The clinical, surgical and light microscopical features of a mesectodermal leiomyoma of the ciliary body are presented. Slit-lamp examination of a 63-year old woman strongly suggested a malignant lesion of the ciliary body and the peripheral choroid. Following cryoretinopexy and argonlaser-photocoagulation, the tumor and the adjacent portion of the cornea, angle structures, iris, ciliary body, choroid and sclera were removed en bloc. The defect was covered by a corneosclerotransplant 14 mm in diameter. Histological examination revealed a well circumscribed tumor of the ciliary body, consisting of sheets of fusiform cells. Intracytoplasmatic filaments gave a positive reaction to an actin antibody (Actin HHF 35 MA 931), demonstrating the smooth muscle origin of the ciliary body tumor by immunocytochemical means.

摘要

本文介绍了一例睫状体中外胚层平滑肌瘤的临床、手术及光学显微镜特征。一名63岁女性经裂隙灯检查强烈提示睫状体及周边脉络膜存在恶性病变。在进行冷冻视网膜固定术和氩激光光凝术后，将肿瘤以及角膜、房角结构、虹膜、睫状体、脉络膜和巩膜的相邻部分整块切除。缺损处用直径14毫米的角膜巩膜移植片覆盖。组织学检查显示睫状体有一个边界清晰的肿瘤，由梭形细胞片组成。胞质内细丝对肌动蛋白抗体（肌动蛋白HHF 35 MA 931）呈阳性反应，通过免疫细胞化学方法证明了睫状体肿瘤的平滑肌起源。