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[巨大卵巢肿瘤切除术后持续性利尿导致缺血性心脏病病例]

[Case of ischemic heart disease resulting from persistent diuresis after giant ovarian tumor resection].

作者信息

Sata Naho, Satoh Masaaki, Seo Norimasa

机构信息

Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, Shimotsuke 329-0498.

出版信息

Masui. 2010 Feb;59(2):231-4.

Abstract

A patient with a giant ovarian tumor weighing about 7 kg was successfully removed by operation. However, her ECG demonstrated ischemic changes after the operation. We report a case of ischemic heart disease due to persistent diuresis after giant ovarian tumor resection. A 75-year-old, 56.5 kg, 143.5 cm woman was admitted to our hospital for ovarian tumor resection. The preoperative ECG showed normal sinus rhythm and no ischemic changes. Both general anesthesia and epidural anesthesia were planed. An epidural catheter was inserted at T12-L1. Anesthesia was induced with propofol 100 mg, fentanyl 100 microg and vecuronium 8 mg under 100% oxygen inhalation. General anesthesia was maintained with sevoflurane while epidural anesthesia was achieved using 0.375% ropivacaine 6 ml. During the operation, blood pressure was 90-110/70-80 mmHg, with SaO2, 100% and heart rate, 70-80 beats x min(-1). The content of tumor was suctioned for 30 minutes. Surgery was successfully finished without any other incidence. After extubation, her ECG changed to atrial fibrillation from normal sinus rhythm and showed ST-T depression. And then her systolic blood pressure became 80 mmHg or below, but we found continued diuresis at about 10 ml x kg(-1) x hr(-1) for over 2 hr. The total of 7 unit vasopressin was intermittently given for vasoconstriction and antidiuresis. Her hemodynamic was immediately restored, and ECG turned to normal ST-T. The patient had uneventful postoperative recovery.

摘要

一名患有重达约7千克巨大卵巢肿瘤的患者通过手术成功切除。然而,术后她的心电图显示有缺血性改变。我们报告一例巨大卵巢肿瘤切除术后因持续性利尿导致的缺血性心脏病病例。一名75岁、体重56.5千克、身高143.5厘米的女性因卵巢肿瘤切除术入院。术前心电图显示窦性心律正常,无缺血性改变。计划采用全身麻醉和硬膜外麻醉。在T12-L1置入硬膜外导管。在吸入100%氧气的情况下,用丙泊酚100毫克、芬太尼100微克和维库溴铵8毫克诱导麻醉。用七氟醚维持全身麻醉,同时用0.375%罗哌卡因6毫升实现硬膜外麻醉。手术过程中,血压为90-110/70-80毫米汞柱,血氧饱和度为100%,心率为70-80次/分钟。肿瘤内容物抽吸30分钟。手术顺利完成,无其他意外情况。拔管后,她的心电图从正常窦性心律变为房颤,并出现ST-T段压低。随后她的收缩压降至80毫米汞柱或更低,但我们发现持续利尿约10毫升·千克⁻¹·小时⁻¹,持续超过2小时。总共间断给予7单位血管加压素以进行血管收缩和抗利尿。她的血流动力学立即恢复,心电图ST-T段恢复正常。患者术后恢复顺利。

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