Center of Excellence, Canandaigua VA Medical Center, Canandaigua, NY 14424, USA.
Suicide Life Threat Behav. 2010 Feb;40(1):14-21. doi: 10.1521/suli.2010.40.1.14.
There are limited prospective data on suicide attempts (SA) during the months following treatment for substance use disorders (SUD), a period of high risk. In an analysis of the Drug Abuse Treatment Outcomes Study, a longitudinal naturalistic multisite study of treated SUDs, variables associated with SA in the 12 months following SUD treatment were examined. Participants included 2,966 patients with one or more SUDs. By 12 months, 77 (2.6%) subjects had attempted suicide. Multivariate logistic regression analyses were used to identify variables associated with SA. Variables collected at baseline that were associated with SA included lifetime histories of SA, suicidal ideation (SI), depression, cocaine as primary substance of use, outpatient methadone treatment, and short-term inpatient treatment. Male sex, older age, and minority race or ethnicity were associated with lower likelihood of SA. After controlling for baseline predictors, variables assessed at 12 months associated with SA included SI during follow-up and daily or more use of cocaine. The data contribute to a small but growing literature of prospective studies of SA among treated SUDs, and suggest that SUDs with cocaine use disorders in particular should be a focus of prevention efforts.
关于物质使用障碍(SUD)治疗后几个月内自杀尝试(SA)的前瞻性数据有限,这是一个高风险时期。在药物滥用治疗结果研究的分析中,这是一项对治疗 SUD 的纵向自然主义多地点研究,对 SUD 治疗后 12 个月内与 SA 相关的变量进行了检查。参与者包括 2966 名患有一种或多种 SUD 的患者。在 12 个月时,77 名(2.6%)受试者曾试图自杀。多变量逻辑回归分析用于确定与 SA 相关的变量。与 SA 相关的基线收集的变量包括自杀史、自杀意念(SI)、抑郁、可卡因作为主要使用物质、门诊美沙酮治疗和短期住院治疗。男性、年龄较大以及少数民族或种族与 SA 的可能性较低相关。在控制基线预测因素后,与 12 个月时 SA 相关的评估变量包括随访期间的 SI 和每天或更多使用可卡因。这些数据为治疗后的 SUD 中 SA 的前瞻性研究的小型但不断增长的文献做出了贡献,并表明可卡因使用障碍的 SUD 尤其应该成为预防工作的重点。