Department of Obstetrics and Gynecology, Central Clinical Hospital of Ministry of Interior and Administration, Warsaw, Poland.
Gynecol Endocrinol. 2010 Jun;26(6):399-403. doi: 10.3109/09513591003632266.
To establish correlations between laboratory findings and clinical symptoms of moderate and severe ovarian hyperstimulation syndrome (OHSS).
A retrospective study.
Department of obstetrics and gynecology, public clinical hospital.
Nineteen women admitted to the public hospital with a diagnosis of OHSS. The procedure of controlled ovarian stimulation (COH) was performed in the private assisted reproductive technology centre.
Blood samples were collected, ultrasound examination of ovaries, abdominal circumference measurement were performed, intravenous crystalloids, plasma expanders such colloids and albumin were given. Correlations between mean laboratory results (haematocrit, c-reactive protein (CRP), white blood count, serum protein, serum albumin), ovarian size in ultrasound examination, abdominal circumference, and amount of albumin and hydroxyethyl starch transfused to the patient were assessed.
Significant correlation was observed between CRP concentration and abdominal circumference measured when the patient was admitted to the department, between CRP concentration and ovarian size measured during ultrasound examination at admission and between CRP concentration and body weight.
CRP can be a potential candidate to an indicator of OHSS severity.
建立实验室检查结果与中重度卵巢过度刺激综合征（OHSS）的临床症状之间的相关性。
回顾性研究。
公立医院妇产科。
19 名在公立医院被诊断为 OHSS 的女性。COH （控制性卵巢刺激）在私立辅助生殖技术中心进行。
采集血样，进行卵巢超声检查，测量腹围，给予静脉晶体、胶体和白蛋白等血浆扩容剂。评估实验室检查均值（红细胞比容、C 反应蛋白（CRP）、白细胞计数、血清蛋白、血清白蛋白）、入院时超声检查的卵巢大小、入院时腹围、白蛋白和羟乙基淀粉输注量与患者之间的相关性。
入院时 CRP 浓度与腹围、入院时超声检查卵巢大小与 CRP 浓度、CRP 浓度与体重之间存在显著相关性。
CRP 可能是 OHSS 严重程度的一个潜在候选指标。
