Kovacic Peter, Hall Marilyn E
Department of Chemistry, San Diego State University, San Diego, CA, USA.
J Recept Signal Transduct Res. 2010 Feb;30(1):1-9. doi: 10.3109/10799890903517939.
Electrochemistry and cell signaling are widely involved in the operation of biochemical systems. This article discusses the relationship of the two, as well as interconnection with a variety of other aspects, such as free radicals, receptors, and stereochemistry. Both endogenous and exogenous agents are involved. The electrochemistry deals with electrostatics, electron transfer, reduction potentials, as well as involvement in membranes, proteins, and neurotransmission. Application of electrostatics is made to cell signaling involving receptor-ligand action, phosphates, sulfates, metal cations, and miscellaneous others. Apparently, energetics play a significant part. Practical and experimental aspects are also addressed.
电化学和细胞信号传导广泛参与生物化学系统的运作。本文讨论了两者之间的关系，以及与自由基、受体和立体化学等其他各个方面的相互联系。内源性和外源性因素均有涉及。电化学涉及静电学、电子转移、还原电位，以及在膜、蛋白质和神经传递中的作用。静电学应用于涉及受体 - 配体作用、磷酸盐、硫酸盐、金属阳离子及其他各种物质的细胞信号传导。显然，能量学起着重要作用。本文还探讨了实际应用和实验方面的内容。
