National Institute for Nutrition and Food Safety, China Center for Disease Control and Prevention, Beijing, China.
BMC Public Health. 2010 Feb 19;10:82. doi: 10.1186/1471-2458-10-82.
Waist circumference has been identified as a valuable predictor of cardiovascular risk in children. The development of waist circumference percentiles and cut-offs for various ethnic groups are necessary because of differences in body composition. The purpose of this study was to develop waist circumference percentiles for Chinese children and to explore optimal waist circumference cut-off values for predicting cardiovascular risk factors clustering in this population.
Height, weight, and waist circumference were measured in 5529 children (2830 boys and 2699 girls) aged 6-12 years randomly selected from southern and northern China. Blood pressure, fasting triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and glucose were obtained in a subsample (n = 1845). Smoothed percentile curves were produced using the LMS method. Receiver-operating characteristic analysis was used to derive the optimal age- and gender-specific waist circumference thresholds for predicting the clustering of cardiovascular risk factors.
Gender-specific waist circumference percentiles were constructed. The waist circumference thresholds were at the 90th and 84th percentiles for Chinese boys and girls respectively, with sensitivity and specificity ranging from 67% to 83%. The odds ratio of a clustering of cardiovascular risk factors among boys and girls with a higher value than cut-off points was 10.349 (95% confidence interval 4.466 to 23.979) and 8.084 (95% confidence interval 3.147 to 20.767) compared with their counterparts.
Percentile curves for waist circumference of Chinese children are provided. The cut-off point for waist circumference to predict cardiovascular risk factors clustering is at the 90th and 84th percentiles for Chinese boys and girls, respectively.
腰围已被确定为儿童心血管风险的一个有价值的预测指标。由于身体成分的差异，制定不同种族群体的腰围百分位和截断值是必要的。本研究的目的是制定中国儿童的腰围百分位，并探讨预测该人群心血管危险因素聚集的最佳腰围截断值。
从中国南方和北方随机抽取 5529 名 6-12 岁儿童（男 2830 名，女 2699 名）测量身高、体重和腰围。在亚组（n=1845）中获得血压、空腹甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和血糖。使用 LMS 方法生成平滑的百分位曲线。使用受试者工作特征分析得出预测心血管危险因素聚集的最佳年龄和性别特异性腰围阈值。
构建了性别特异性腰围百分位。中国男童和女童的腰围截断值分别为第 90 百分位和第 84 百分位，敏感性和特异性范围为 67%至 83%。高于截断值的男孩和女孩中心血管危险因素聚集的比值比为 10.349（95%置信区间 4.466 至 23.979）和 8.084（95%置信区间 3.147 至 20.767）。
提供了中国儿童腰围百分位曲线。预测心血管危险因素聚集的腰围截断值分别为中国男童和女童的第 90 百分位和第 84 百分位。
