Department of Biochemistry, University of Ilorin, Ilorin, Nigeria.
Food Chem Toxicol. 2010 May;48(5):1250-4. doi: 10.1016/j.fct.2010.02.018. Epub 2010 Feb 17.
Effects of Aspergillus niger-fermented Terminalia catappa seed meal-based diet on the activities of alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST) and gamma-glutamate transferase (gamma-GT) in the crop, small intestine, gizzard, heart, liver and serum of broiler chicks were investigated. Milled T. catappa seed was inoculated with spores of A.niger (2.21 x 10(4) spores per ml) for 3 weeks. Forty-five day-old broiler chicks weighing between 27.62 and 36.21 g, were divided into three groups. The first group was fed soybean-based (control) diet; the second on raw T. catappa seed meal-based diet; and the third on A. niger-fermented T. catappa seed meal-based diet for 7 weeks. The results revealed a significantly increased (p<0.05) activity of ALP in the tissues. Contrarily, there were significant reductions (p<0.05) in the activities of ALP, ALT, AST and gamma-GT in the liver and heart of the broilers fed the raw T. catappa seed meal-based diet while there were significant increase (p<0.05) in the activities of these enzymes in the serum of the broilers in this group. The data obtained showed that A. niger-fermented T. catappa seed meal reduced the toxic effects of the raw seed meal on the tissues of broiler chicks.
黑曲霉发酵诃子籽粕日粮对肉鸡嗉囊、肠道、肌胃、心脏、肝脏和血清中碱性磷酸酶（ALP）、丙氨酸转氨酶（ALT）、天门冬氨酸转氨酶（AST）和γ-谷氨酰转移酶（γ-GT）活性的影响进行了研究。将诃子籽粉碎后，用黑曲霉孢子（2.21×10(4)个孢子/毫升）接种，发酵 3 周。45 日龄体重在 27.62 到 36.21 克之间的肉鸡被分为三组。第一组饲喂大豆基础日粮（对照组）；第二组饲喂生诃子籽粕日粮；第三组饲喂黑曲霉发酵诃子籽粕日粮，共 7 周。结果表明，组织中 ALP 的活性显著增加（p<0.05）。相反，饲喂生诃子籽粕日粮的肉鸡的肝脏和心脏中 ALP、ALT、AST 和 γ-GT 的活性显著降低（p<0.05），而该组肉鸡血清中这些酶的活性显著升高（p<0.05）。研究结果表明，黑曲霉发酵诃子籽粕降低了生诃子籽粕对肉鸡组织的毒性作用。
