Department of Hepatology and Gastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Gastrointest Endosc. 2010 Apr;71(4):806-11. doi: 10.1016/j.gie.2009.10.058. Epub 2010 Feb 18.
Effective and safe access site closure is critical for clinical application of natural orifice transluminal endoscopic surgery.
The current study evaluated a simple novel technique of gastrotomy closure.
Feasibility study with a survival animal model.
Animal laboratory.
Ten female domestic pigs.
Endoscopic closure of a gastrotomy incision was evaluated in 10 pigs in a survival study. A standard double-channel endoscope was advanced into the peritoneal cavity through an incision made by a needle-knife and an 18-mm dilation balloon. After peritoneoscopy and salpingectomy, gastric closure was performed by using an endoscopic grasper and sequential application of 2 endoloops. After a follow-up period of 1 to 3 weeks, the pigs were killed for postmortem examination.
Feasibility, efficiency, and safety of a novel closure technique.
Correct positioning and delivery of endoloops was achieved in all animals in a median time of 17 minutes (range 13-25 minutes). All animals survived without complications. Postmortem examination demonstrated patent full-thickness gastric closure without any evidence of infection.
Feasibility study with a small number of subjects in a porcine model.
Double endoloop technique represents a novel, simple, safe, and efficient means of gastric access site closure in natural orifice transluminal endoscopic surgery.
有效的、安全的入路关闭对于经自然腔道内镜手术的临床应用至关重要。
本研究评估了一种简单的新型胃造口关闭技术。
具有生存动物模型的可行性研究。
动物实验室。
10 只雌性家猪。
在生存研究中，评估了 10 只猪的内镜胃造口闭合情况。标准双通道内镜通过针刀和 18mm 扩张球囊制成的切口进入腹腔。在腹膜检查和输卵管切除术之后，通过使用内镜抓钳和连续应用 2 个内镜套扎环进行胃闭合。在 1 至 3 周的随访期后，将猪处死进行尸检。
新型闭合技术的可行性、效率和安全性。
所有动物的内镜套扎环均能在中位数 17 分钟（范围 13-25 分钟）的时间内正确定位和输送。所有动物均存活，无并发症。尸检显示，完全厚度的胃闭合，无感染证据。
在猪模型中进行的少数对象可行性研究。
双内镜套扎环技术是经自然腔道内镜手术中一种新型、简单、安全、有效的胃入路关闭方法。
