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喉和咽部的放射剂量-体积效应。

Radiation dose-volume effects in the larynx and pharynx.

机构信息

Fondazione IRCCS-Istituto Nazionale dei Tumori, Milan, Italy.

出版信息

Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S64-9. doi: 10.1016/j.ijrobp.2009.03.079.

DOI:10.1016/j.ijrobp.2009.03.079
PMID:20171520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2833104/
Abstract

The dose-volume outcome data for RT-associated laryngeal edema, laryngeal dysfunction, and dysphagia, have only recently been addressed, and are summarized. For late dysphagia, a major issue is accurate definition and uncertainty of the relevant anatomical structures. These and other issues are discussed.

摘要

放射性治疗相关的喉水肿、喉功能障碍和吞咽困难的剂量-体积结果数据最近才得到解决,并进行了总结。对于晚期吞咽困难,一个主要问题是相关解剖结构的准确定义和不确定性。这些和其他问题进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5167/2833104/baba57a6b9ff/nihms-163446-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5167/2833104/baba57a6b9ff/nihms-163446-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5167/2833104/baba57a6b9ff/nihms-163446-f0001.jpg

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本文引用的文献

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Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):915-23. doi: 10.1016/j.ijrobp.2009.04.087. Epub 2009 Sep 9.
2
Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy.喉剂量可预测调强放疗后的吞咽并发症。
Int J Radiat Oncol Biol Phys. 2008 Nov 15;72(4):1110-8. doi: 10.1016/j.ijrobp.2008.02.048. Epub 2008 May 28.
3
Aspiration in chemoradiated patients with head and neck cancer.头颈部癌放化疗患者的误吸
Arch Otolaryngol Head Neck Surg. 2007 Dec;133(12):1289-95. doi: 10.1001/archotol.133.12.1289.
4
Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship.口咽癌患者的吞咽障碍明显受到对上咽缩肌和中咽缩肌的放射治疗剂量的影响:一种剂量效应关系。
Radiother Oncol. 2007 Oct;85(1):64-73. doi: 10.1016/j.radonc.2007.07.009. Epub 2007 Aug 21.
5
Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: frequency, intensity and correlation with dose and volume parameters.下咽癌放疗后的晚期吞咽功能障碍和吞咽困难:发生率、严重程度及其与剂量和体积参数的相关性
Radiother Oncol. 2007 Oct;85(1):74-82. doi: 10.1016/j.radonc.2007.06.004. Epub 2007 Jul 27.
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Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures.旨在减少吞咽困难的头颈部癌调强放疗:吞咽结构的早期剂量效应关系
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