Pig Research Center, Instituto Tecnológico Agrario de Castilla y León, Consejería de Agricultura y Ganadería, Junta de Castilla y León, Ctra. Riaza-Toro s/n., Hontalbilla (Segovia), Spain.
Theriogenology. 2010 Jul 1;74(1):67-74. doi: 10.1016/j.theriogenology.2009.12.020. Epub 2010 Feb 19.
Cytogenetic analysis of 58 boars at an artificial insemination (AI) centre revealed the presence of a reciprocal chromosome translocation, rcp(1;11)(q-;p+), in two Duroc boars. Pedigree analysis of these two boars suggested familial transmission of the chromosome rearrangement. The reproductive consequences of this translocation were determined in a herd of sows that had received semen doses from these and other boars. All sows underwent multiple AI, with different groups established retrospectively depending on the percentage of semen doses provided by the carrier boars ([number of carrier boar doses/total number doses provided] x 100): 0%, 25%, 50%, 75%, 100%. The fertility rates (percentage of successful multiple AIs/total multiple AIs) recorded for multiple AI including semen doses from the carrier boars were not significantly different from those recorded when all semen doses were supplied by normal-karyotype boars. A reduction in litter size of 29.38% was observed, however, in litters sired by one of the carrier boars when its participation in multiple AI was 100%. The number of live-born piglets per litter gradually decreased (P<0.05) as the percentage participation in multiple AI (25, 50, or 75%) of the carrier boar increased. In addition, both carrier boars sired some piglets with signs of cleft palate and complex malformations of the front legs; these died soon after birth. In conclusion, the boars carrying the translocation rcp(1;11)(q-;p+) showed reduced reproductive performance.
在一个人工授精（AI）中心对 58 头公猪进行细胞遗传学分析，发现两头杜洛克公猪存在相互易位染色体，rcp(1;11)(q-;p+)。这两头公猪的系谱分析表明该染色体重排存在家族遗传。通过接受这些公猪和其他公猪精液剂量的母猪群，确定了该易位的生殖后果。所有母猪都接受了多次 AI，根据携带公猪的精液剂量比例（[携带公猪的精液剂量数/提供的总精液剂量数] x 100），建立了不同的回溯组：0%、25%、50%、75%、100%。包括携带公猪精液剂量在内的多次 AI 的受孕率（成功多次 AI 的百分比/总多次 AI 次数）与正常核型公猪提供的所有精液剂量的受孕率没有显著差异。然而，当其中一个携带公猪的多次 AI 参与率为 100%时，其后代的窝产仔数减少了 29.38%。当携带公猪的多次 AI 参与率为 25%、50%或 75%时，每窝活产仔数逐渐减少（P<0.05）。此外，两头携带公猪都有一些产仔前腿有裂腭和复杂畸形的迹象，这些猪仔出生后不久就死亡。总之，携带 rcp(1;11)(q-;p+)易位的公猪表现出繁殖性能下降。
