基于调强适形放疗的容积旋转调强放疗计划优化方法。
IMRT-based optimization approaches for volumetric modulated single arc radiotherapy planning.
机构信息
Department of Radiotherapy, University Hospital Leuven, Leuven, Belgium.
出版信息
Radiother Oncol. 2010 May;95(2):149-52. doi: 10.1016/j.radonc.2010.01.012. Epub 2010 Feb 18.
PMID:20171750
Abstract
This paper reports on an evaluation of 5 RapidArc optimization approaches vs IMRT. This study includes 11 patients with adenocarcinoma of the prostate. Rectal Normal Tissue Complication Probability is used as a constraint in a dose escalation. RapidArc rectal NTCP's are lower than those of IMRT (p = 0.007). This allows a mean dose escalation of 2.1 Gy([0.7 Gy,3.5 Gy]).
摘要
本文报告了 5 种 RapidArc 优化方法与调强放疗（IMRT）的对比评估。该研究纳入了 11 例前列腺腺癌患者。直肠正常组织并发症概率（rectal normal tissue complication probability，NTCP）被用作剂量递增的限制条件。RapidArc 的直肠 NTCP 低于 IMRT（p=0.007）。这使得平均剂量递增 2.1Gy（[0.7Gy，3.5Gy]）成为可能。
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