Department of Oncology, St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, Surrey, UK.
Br J Radiol. 2011 Nov;84(1007):967-96. doi: 10.1259/bjr/22373346.
Volumetric modulated arc therapy (VMAT) is a novel radiation technique, which can achieve highly conformal dose distributions with improved target volume coverage and sparing of normal tissues compared with conventional radiotherapy techniques. VMAT also has the potential to offer additional advantages, such as reduced treatment delivery time compared with conventional static field intensity modulated radiotherapy (IMRT). The clinical worldwide use of VMAT is increasing significantly. Currently the majority of published data on VMAT are limited to planning and feasibility studies, although there is emerging clinical outcome data in several tumour sites. This article aims to discuss the current use of VMAT techniques in practice and review the available data from planning and clinical outcome studies in various tumour sites including prostate, pelvis (lower gastrointestinal, gynaecological), head and neck, thoracic, central nervous system, breast and other tumour sites.
容积旋转调强放疗（VMAT）是一种新的放射治疗技术，与传统放疗技术相比，它可以实现高度适形的剂量分布，提高靶区覆盖率，并保护正常组织。VMAT 还有可能提供额外的优势，例如与传统静态强度调制放疗（IMRT）相比，治疗时间更短。VMAT 在全球范围内的临床应用正在显著增加。目前，大多数关于 VMAT 的已发表数据仅限于计划和可行性研究，尽管在几个肿瘤部位已经有新的临床结果数据。本文旨在讨论 VMAT 技术在实践中的当前应用，并回顾在包括前列腺、骨盆（下胃肠道、妇科）、头颈部、胸部、中枢神经系统、乳腺和其他肿瘤部位在内的各种肿瘤部位的计划和临床结果研究中的现有数据。
