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Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells.

作者信息

Garcia S, Bernad A, Martín M C, Cigudosa J C, Garcia-Castro J, de la Fuente R

出版信息

Exp Cell Res. 2010 May 15;316(9):1648-50. doi: 10.1016/j.yexcr.2010.02.016. Epub 2010 Feb 18.

DOI:10.1016/j.yexcr.2010.02.016

PMID:20171963

Abstract

摘要

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Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells.

作者信息

Garcia S, Bernad A, Martín M C, Cigudosa J C, Garcia-Castro J, de la Fuente R

出版信息

Exp Cell Res. 2010 May 15;316(9):1648-50. doi: 10.1016/j.yexcr.2010.02.016. Epub 2010 Feb 18.

DOI:10.1016/j.yexcr.2010.02.016

PMID:20171963

Abstract

摘要

相似文献

Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells.

Exp Cell Res. 2010 May 15;316(9):1648-50. doi: 10.1016/j.yexcr.2010.02.016. Epub 2010 Feb 18.

Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells.

Int J Oncol. 2011 Jul;39(1):5-11. doi: 10.3892/ijo.2011.1029. Epub 2011 May 3.

Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation.

Cancer Res. 2009 Jul 1;69(13):5331-9. doi: 10.1158/0008-5472.CAN-08-4630. Epub 2009 Jun 9.

In vitro transformation of mesenchymal stem cells by oncogenic H-rasVal12.

Biochem Biophys Res Commun. 2007 Feb 2;353(1):60-6. doi: 10.1016/j.bbrc.2006.11.137. Epub 2006 Dec 6.

Spontaneous transformation of cynomolgus mesenchymal stem cells in vitro: further confirmation by short tandem repeat analysis.

Exp Cell Res. 2012 Mar 10;318(5):435-40. doi: 10.1016/j.yexcr.2011.12.012. Epub 2011 Dec 20.

Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC).

Cell Commun Signal. 2018 Jan 5;16(1):2. doi: 10.1186/s12964-018-0215-4.

Alterations of cytological and karyological profile of human mesenchymal stem cells during in vitro culturing.

Bull Exp Biol Med. 2010 Dec;150(1):125-30. doi: 10.1007/s10517-010-1086-x.

Human mesenchymal precursors derived from embryonic stem cells have specialized differentiation potential and are not tumorigenic.

Cancer Biol Ther. 2005 Aug;4(8):i. doi: 10.4161/cbt.4.8.2002.

Spontaneous differentiation of murine bone marrow-derived mesenchymal stem cells into adipocytes without malignant transformation after long-term culture.

Cells Tissues Organs. 2010;191(3):185-92. doi: 10.1159/000240246. Epub 2009 Sep 18.

p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells.

Exp Cell Res. 2009 Dec 10;315(20):3598-610. doi: 10.1016/j.yexcr.2009.08.004. Epub 2009 Aug 15.

引用本文的文献

Role of Mesenchymal Stem/Stromal Cells (MSCs) and MSC-Derived Extracellular Vesicles (EVs) in Prevention of Telomere Length Shortening, Cellular Senescence, and Accelerated Biological Aging.

Bioengineering (Basel). 2024 May 21;11(6):524. doi: 10.3390/bioengineering11060524.

Evaluation of the reproducibility and positive controls of cellular immortality test for the detection of immortalized cellular impurities in human cell-processed therapeutic products.

Regen Ther. 2022 Nov 2;21:540-546. doi: 10.1016/j.reth.2022.10.009. eCollection 2022 Dec.

Highly Sensitive Detection of Human Pluripotent Stem Cells by Loop-Mediated Isothermal Amplification.

Stem Cell Rev Rep. 2022 Dec;18(8):2995-3007. doi: 10.1007/s12015-022-10402-3. Epub 2022 Jun 3.

Stem cell therapy applied for digestive anastomosis: Current state and future perspectives.

World J Stem Cells. 2022 Jan 26;14(1):117-141. doi: 10.4252/wjsc.v14.i1.117.

Novel cell sources for bone regeneration.

MedComm (2020). 2021 May 4;2(2):145-174. doi: 10.1002/mco2.51. eCollection 2021 Jun.

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Cells. 2021 Aug 13;10(8):2086. doi: 10.3390/cells10082086.

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Stem Cells Transl Med. 2020 Dec;9(12):1500-1508. doi: 10.1002/sctm.19-0431. Epub 2020 Aug 31.

Safety of Technique and Procedure of Stromal Vascular Fraction Therapy: From Liposuction to Cell Administration.

Scientifica (Cairo). 2020 Jul 4;2020:2863624. doi: 10.1155/2020/2863624. eCollection 2020.

Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges.

Pharmaceutics. 2019 Oct 24;11(11):552. doi: 10.3390/pharmaceutics11110552.

A Comparison of Phenotypic and Functional Properties of Mesenchymal Stromal Cells and Multipotent Adult Progenitor Cells.

Front Immunol. 2019 Aug 28;10:1952. doi: 10.3389/fimmu.2019.01952. eCollection 2019.