支气管热成形术。

Bronchial thermoplasty.

机构信息

Firestone Institute for Respiratory Health, St Joseph's Healthcare Hamilton, 50 Charlton Avenue E, Hamilton, ON L8N 4A6, Canada.

出版信息

Clin Chest Med. 2010 Mar;31(1):135-40,Table of Contents. doi: 10.1016/j.ccm.2009.09.003.

DOI:10.1016/j.ccm.2009.09.003

PMID:20172439

Abstract

Asthma, by definition is a variable disease. When there is more than normal natural variation in airflow, asthma can be provoked by a wide range of stimuli that include infectious, allergic, and environmental agents. Bronchoconstriction determines much of the short-term variability in airflow that characterizes asthma. Current treatments do not redress the excess smooth muscle mass that is present in the remodeled airway in chronic asthma. Thus, it is intriguing to consider the potential contribution of bronchial thermoplasty (a procedure that involves controlled heat treatment to reduce the mass of the airway smooth muscle) as an effective therapy for poorly controlled asthma.

摘要

哮喘，从定义上讲，是一种多变的疾病。当气流的自然变化超过正常水平时，哮喘可能会受到多种刺激的诱发，包括感染、过敏和环境因素。支气管收缩决定了哮喘特征性的气流短期可变性的大部分。目前的治疗方法并不能纠正慢性哮喘中重塑气道中存在的平滑肌过度增生。因此，支气管热成形术（一种通过控制热疗来减少气道平滑肌质量的程序）作为一种有效的治疗方法，对于控制不佳的哮喘来说，具有潜在的治疗价值。