Ramírez-Plaza César P, Rodríguez-Cañete Alberto, Domínguez-López Marta E, Valle-Carbajo Marta, Jiménez-Mazure Carolina, Marín-Camero Naiara, Gallego-Perales José L, Santoyo-Santoyo Julio
Servicio de Cirugía General, Digestiva y Trasplantes, Hospital Regional Universitario de Málaga Carlos Haya, Málaga, España.
Endocrinol Nutr. 2010 Jan;57(1):22-7. doi: 10.1016/S1575-0922(10)70005-X.
After the first reports in 1992, laparoscopic adrenalectomy (LA) has evolved technically until becoming the standard approach for the treatment of most of the adrenal gland diseases.
Retrospective and descriptive study of 67 patients who underwent 68 LA between January-1998 and December-2008 in the Laparoscopic Surgery Unit of the General and Digestive Surgery Service in a third level hospital (only one case of bilateral LA). The group was divided in 2 periods, P-1 (1998-2003, 22 cases) and P-2 (2004-2008, 45 cases), which have been compared to evaluate the evolution of the LA technique.
Indications for LA were: 19 incidentalomas, 19 primary hyperaldosteronism, 18 pheocromocitoms, 5 cases of symptomatic and non-functioning adrenal masses, 4 Cushing adenomas and 2 metastases. There was no mortality, only 4 patients had minor complications (6%) and conversion rate was only 3% (2 cases). Mean size of adrenal glands resected was 3.83 cm and the mean operative time was 86 minutes. Mean postoperative hospital stay was 3 days and in P-2 seventeen patients were discharged on an outpatient basis (hospital stay less than 23 hours).
In our experience, LA for the treatment of adrenal diseases has shown to be safe, effective and reproducible with low complications and excellent tolerance by patients. When the learning curve is overcome, hospital stay and operative time clearly decrease. As a consequence, LA can be planned in selected cases as outpatient surgery with good results.
自1992年首次报道以来,腹腔镜肾上腺切除术(LA)在技术上不断发展,直至成为治疗大多数肾上腺疾病的标准方法。
对1998年1月至2008年12月期间在一家三级医院普通及消化外科腹腔镜手术科室接受68例LA手术的67例患者进行回顾性描述性研究(仅1例双侧LA)。该组患者分为两个时期,P-1期(1998 - 2003年,22例)和P-2期(2004 - 2008年,45例),通过比较这两个时期来评估LA技术的发展。
LA的适应证为:19例肾上腺意外瘤、19例原发性醛固酮增多症、18例嗜铬细胞瘤、5例有症状的无功能肾上腺肿块、4例库欣腺瘤和2例转移瘤。无死亡病例,仅4例患者出现轻微并发症(6%),中转开放手术率仅为3%(2例)。切除肾上腺的平均大小为3.83 cm,平均手术时间为86分钟。术后平均住院时间为3天,在P-2期,17例患者门诊出院(住院时间少于23小时)。
根据我们的经验,LA治疗肾上腺疾病已被证明是安全、有效且可重复的,并发症少,患者耐受性良好。当克服学习曲线后,住院时间和手术时间明显缩短。因此,对于部分病例可考虑将LA作为门诊手术,效果良好。