Department of Oral & Maxillofacial Surgery, Faculty of Medicine, University of Technology Dresden, Germany.
Int J Oral Maxillofac Surg. 2010 Jun;39(6):585-92. doi: 10.1016/j.ijom.2010.01.015. Epub 2010 Feb 20.
The aim of this animal study was to investigate and compare the osseointegration of zirconia and titanium dental implants. 14 one-piece zirconia implants and 7 titanium implants were inserted into the mandibles of 7 minipigs. The zirconia implants were alternately placed submerged and non-submerged. To enable submerged healing, the supraosseous part was removed, using a diamond saw. The titanium implants were all placed submerged. After a healing period of 4 weeks, a histological analysis of the soft and hard tissue and a histomorphometric analysis of the bone-implant contact (BIC) and relative peri-implant bone-volume density (rBVD; relation to bone-volume density of the host bone) was performed. Two zirconia implants were found to be loose. All other implants were available for evaluation. For submerged zirconia and titanium implants, the implant surface showed an intimate connection to the neighbouring bone, with both types achieving a BIC of 53%. For the non-submerged zirconia implants, some crestal epithelial downgrowth could be detected, with a resultant BIC of 48%. Highest rBVD values were found for submerged zirconia (80%), followed by titanium (74%) and non-submerged zirconia (63%). The results suggest that unloaded zirconia and titanium implants osseointegrate comparably, within the healing period studied.
本动物研究旨在探讨和比较氧化锆和钛牙科种植体的骨整合情况。将 14 个一体式氧化锆种植体和 7 个钛种植体植入 7 只小型猪的下颌骨中。氧化锆种植体被交替地埋入和非埋入。为了实现埋入式愈合，使用金刚石锯将超骨部分切除。所有钛种植体均埋入。愈合期 4 周后，对软组织和硬组织进行组织学分析，并对骨-种植体接触（BIC）和相对种植体周围骨体积密度（rBVD；与宿主骨骨密度的关系）进行组织形态计量学分析。发现有两个氧化锆种植体松动。其余所有种植体均可进行评估。对于埋入式氧化锆和钛种植体，种植体表面与相邻骨之间显示出紧密的连接，两种类型的 BIC 均达到 53%。对于非埋入式氧化锆种植体，可检测到一些牙骨质上皮向下生长，导致 BIC 为 48%。埋入式氧化锆的 rBVD 值最高（80%），其次是钛（74%）和非埋入式氧化锆（63%）。结果表明，在研究的愈合期内，未负重的氧化锆和钛种植体具有相当的骨整合能力。
