Department of Computer Science and Engineering, Tezpur University, Tezpur, Assam 784 028, India.
Microbiol Res. 2010 Oct 20;165(8):609-16. doi: 10.1016/j.micres.2009.12.003. Epub 2010 Feb 21.
We have done a comparative study of tRNA diversity and total tRNA genes among different strains of bacteria with respect to the optimum growth temperature of the cells. Our observation suggests that higher tRNA diversity usually occurs in thermophiles in comparison to non-thermophiles. Among psychrophiles total tRNA was observed to be more than two-fold higher than in the non-psychrophiles. Though tRNA diversity and total tRNA have recently been shown to be affected by an organism's genomic GC% and growth rate, this work is the first report on growth temperature affecting these features in bacteria. This work extends the list of molecular features undergoing adaptation due to growth temperature and supports the view that growth temperature acts as a selecting factor at the molecular level during evolution.
我们针对细胞的最适生长温度，对不同细菌菌株的 tRNA 多样性和总 tRNA 基因进行了比较研究。我们的观察表明，与非嗜热菌相比，嗜热菌通常具有更高的 tRNA 多样性。在嗜冷菌中，总 tRNA 比非嗜冷菌高两倍以上。尽管 tRNA 多样性和总 tRNA 最近已被证明受生物体基因组 GC%和生长速度的影响，但这项工作首次报告了生长温度对这些细菌特征的影响。这项工作扩展了由于生长温度而发生适应性的分子特征列表，并支持了生长温度在进化过程中作为分子水平选择因素的观点。
