Department of Vascular and Endovascular Surgery, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
J Vasc Interv Radiol. 2010 Apr;21(4):465-9. doi: 10.1016/j.jvir.2009.11.018. Epub 2010 Feb 20.
To report a series of patients with symptomatic internal carotid artery (ICA) occlusion treated with angioplasty and stents.
From a consecutive series of 50 patients experiencing neurologic ischemic symptoms and shown by conventional ultrasonography (US) to have a total ICA occlusion, 16 patients (ages 45-79 years; mean, 63 y; 10 men) were selected between August 2006 to September 2008 to be treated with angioplasty based on discovery of an open ICA distal to the occlusion through contrast-enhanced echo Doppler imaging and/or multislice contrast computed tomography (CT). Angioplasty and stent placement were performed under cerebral protection. Follow-up duplex imaging was performed at 14 days and 3 months and every 6 months thereafter and CT follow-up was performed at 2-9 months; the mean follow-up period was 9.9 months.
Lesion crossing and stent placement was successful in 13 of 16 patients. There were no deaths, conversions, cardiac complications, or major strokes. One patient had a transient mild hemiparesis in the upper limb, with total recovery in 3 months. At follow-up, all 13 patients with a good initial result remained with patent arterial lumens and resolution of neurologic ischemic symptoms. After 2-9 months, ICAs with a "string sign" had calibers close or equal to those of normal arteries.
Angioplasty with stent placement is an effective treatment with a low morbidity rate for selected patients who continue to experience neurologic ischemic symptoms despite US findings of total occlusion of the ICA.
报告一系列接受血管成形术和支架治疗的症状性颈内动脉(ICA)闭塞患者。
在 50 例经历神经缺血症状且常规超声(US)显示 ICA 完全闭塞的连续患者系列中,2006 年 8 月至 2008 年 9 月间选择了 16 例(年龄 45-79 岁;平均 63 岁;10 例男性)患者,通过增强型 echo 多普勒成像和/或多层对比 CT 发现闭塞段远端开放 ICA 而选择接受血管成形术和支架置入治疗。在脑保护下进行血管成形术和支架置入术。在术后 14 天和 3 个月进行双功超声随访,此后每 6 个月随访一次,并在 2-9 个月进行 CT 随访;平均随访时间为 9.9 个月。
16 例患者中有 13 例成功完成了病变跨越和支架置入。无死亡、转换、心脏并发症或重大卒中。1 例患者上肢出现短暂性轻度偏瘫,3 个月完全恢复。随访时,所有 13 例初始结果良好的患者动脉管腔均保持通畅,神经缺血症状得到缓解。2-9 个月后,ICA 出现“串珠样”改变,管腔直径接近或等于正常动脉。
对于尽管 US 显示 ICA 完全闭塞但仍持续出现神经缺血症状的特定患者,血管成形术和支架置入是一种有效且发病率较低的治疗方法。