Marlow Nicole M, Halpern Michael T, Pavluck Alexandre L, Ward Elizabeth M, Chen Amy Y
of Biostatistics and Epidemiology at the Medical University of South Carolina, SC 29425, USA.
J Health Care Poor Underserved. 2010 Feb;21(1):112-31. doi: 10.1353/hpu.0.0253.
This study expands on a previous report (focusing on health insurance status and race/ethnicity) to present effects of age, socioeconomic status, hospital type, and other factors (e.g., type of Medicaid and Medicare coverage, insurance-by-race/ethnicity interactions) on advanced-stage (III/IV) at prostate cancer diagnosis. Invasive (Stages I-IV) prostate cancer cases diagnosed during 1998-2004 were extracted from the National Cancer Database (N=687,464). Independent of health-insurance and race/ethnicity, socioeconomic status was a significant predictor of advanced stage at diagnosis, with patients residing in areas with lower socioeconomic characteristics having significantly increased odds. Those treated at community-cancer-centers had significantly decreased odds (versus teaching/research-facilities). Significantly increased odds were also observed among uninsured-Blacks, Medicare-insured-Blacks, Medicaid-insured-Blacks, Medicare-insured-Hispanics, and Medicare-insured-other-racial/ethnic-minorities 65 years old and older (versus corresponding White-populations). The impact of prostate cancer screening on reducing mortality remains debatable. Still, our results suggest improvements in multiple factors that affect access-to-care may achieve earlier diagnosis and, therefore, a potentially more treatable disease.
本研究在先前一份报告(聚焦于健康保险状况及种族/族裔)的基础上进行拓展,以呈现年龄、社会经济地位、医院类型及其他因素(如医疗补助和医疗保险覆盖类型、按种族/族裔划分的保险交互作用)对前列腺癌诊断时晚期(III/IV期)的影响。1998年至2004年期间诊断出的浸润性(I-IV期)前列腺癌病例从国家癌症数据库中提取(N = 687,464)。独立于健康保险和种族/族裔因素,社会经济地位是诊断时处于晚期的重要预测因素,居住在社会经济特征较低地区的患者患病几率显著增加。在社区癌症中心接受治疗的患者患病几率显著降低(与教学/研究机构相比)。在未参保黑人、医疗保险参保黑人、医疗补助参保黑人、医疗保险参保西班牙裔以及65岁及以上的医疗保险参保其他种族/族裔少数群体中(与相应的白人人群相比),患病几率也显著增加。前列腺癌筛查对降低死亡率的影响仍存在争议。尽管如此,我们的结果表明,在影响医疗可及性的多个因素方面取得改善可能实现更早诊断,从而使疾病可能更易于治疗。