非洲爪蟾的八聚体转录因子-1（Oct-1）不与某些组蛋白H2B基因启动子八聚体基序结合，而一种新型八聚体结合因子对这些基序具有高亲和力。
Xenopus laevis Oct-1 does not bind to certain histone H2B gene promoter octamer motifs for which a novel octamer-binding factor has high affinity.
作者信息
Smith D P, Old R W
机构信息
Department of Biological Sciences, University of Warwick, Coventry, UK.
出版信息
Nucleic Acids Res. 1991 Feb 25;19(4):815-21. doi: 10.1093/nar/19.4.815.
Abstract
Oct-1 and a second, previously unidentified octamer-binding protein (Oct-R) have been identified in extracts of Xenopus laevis oocytes and embryos. Oct-1 does not bind to the octamer motif associated with certain Xenopus laevis histone H2B gene promoters, whereas Oct-R binds well to this motif, but only in the sequence context of the H2B gene promoter.
摘要
在非洲爪蟾卵母细胞和胚胎提取物中已鉴定出Oct-1和另一种先前未鉴定的八聚体结合蛋白（Oct-R）。Oct-1不与某些非洲爪蟾组蛋白H2B基因启动子相关的八聚体基序结合，而Oct-R能很好地结合该基序，但仅在H2B基因启动子的序列背景下。
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