Department of Otolaryngology, VU University Medical Center, Amsterdam, The Netherlands.
Curr Opin Oncol. 2010 May;22(3):186-93. doi: 10.1097/CCO.0b013e3283380009.
This paper reviews the advances in surgery in head and neck cancer patients.
Sentinel node biopsy is a promising diagnostic technique to detect occult lymph node metastases, especially in oral carcinomas. Fludeoxyglucose-PET seems to be useful in detecting recurrent (laryngeal) carcinoma after radiotherapy. The role of fludeoxyglucose-PET to detect residual disease in the neck after radiotherapy with or without chemotherapy is not yet clear. The armamentarium of reconstructive surgery is still expanding. Endonasal endoscopic, robotic surgery and image-guided surgery are used as minimal invasive surgery in selected patients. Other advances include photodynamic therapy, ultrasonic surgery and mechanical sutures.
New diagnostic techniques are used to avoid futile extensive surgery. Technical improvements have been made to treat head and neck cancer patients with minimal invasive surgery. Large prospective trials are needed to determine the indications for each technique.
本文综述了头颈部癌症患者外科治疗的进展。
前哨淋巴结活检术是一种很有前途的诊断技术,可用于检测隐匿性淋巴结转移,特别是在口腔癌中。氟脱氧葡萄糖-PET 似乎可用于检测放疗后复发性(喉)癌。氟脱氧葡萄糖-PET 在检测放疗后有无化疗的颈部残留疾病中的作用尚不清楚。重建外科的手段仍在不断扩展。鼻内镜、机器人手术和图像引导手术被用于某些患者的微创手术。其他进展包括光动力疗法、超声手术和机械缝合。
新的诊断技术被用于避免无效的广泛手术。技术改进使头颈部癌症患者能够接受微创手术治疗。需要进行大型前瞻性试验来确定每种技术的适应证。